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18 June 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Christine Engelbrecht from the Agricultural Research Council
Dr Christine Engelbrecht from the Agricultural Research Council presented the keynote lecture on climate dynamics, predicting that El Niños will double in frequency towards the end of the century.

The world will need nearly double the current food supply by 2050 to feed an ever-increasing world population. This is a mammoth, almost impossible task.

Building on knowledge

According to UFS Rector and Vice-Chancellor, Prof Francis Petersen, if we approach challenges such as these with scientific level-headedness, systematically build on knowledge and experience gained, and draw on similar inputs from other specialist fields, the seemingly impossible becomes possible.

“To what extent do we integrate our knowledge across sectors – within the university and outside the university; on the continent as well as globally?” he asked the 300-plus delegates, which included animal scientists, students, and various other role players in the livestock sector, at the 51st South African Society of Animal Science (SASAS) congress on the Bloemfontein Campus of the University of the Free State (UFS). 

Willingness to adapt to new strategies


The theme of this year’s congress was: Managing the ecological footprint of livestock through efficient production. The congress provided a platform for discussions on the impact of livestock production – bringing in elements of critical thinking, as well as the willingness to adopt new strategies. 

During the congress, workshops on topics such as silage, predation management, intensive sheep production, prickly-pear utilisation, and animal welfare provided delegates with the opportunity to discuss challenges faced by the South African livestock producer.

Dr Christine Engelbrecht (Meteorology) from the Agricultural Research Council presented the first keynote address, focusing on climate dynamics. 

“We have high-impact weather systems across Southern Africa. It is projected that strong El Niños are to double in frequency towards the end of the 21st century,” said Dr Engelbrecht. 

She further predicted temperature increases of between 4 and 7 degrees Celsius in the interior before the end of the century. Over the Free State, Northern Cape, and North-West Province, we can expect shorter frost seasons, significant increases in maximum temperatures for both summer and winter, as well as more frequent El Niño-induced droughts. 

Ecological footprint of food

Improved production outputs need to be achieved by using less land, water, and available energy, while ensuring that the degradation and pollution of natural resources are limited. A scientific approach would be a viable option to improve the efficiency of livestock production.

SASAS President, Prof Este van Marle-Köster from the University of Pretoria, pointed out that all food had an ecological impact.

Dr Frikkie Maré, Head of the Department of Agricultural Economics at the UFS, presented a keynote lecture on managing the footprint of beef through efficient production. Comparing the water footprint of different cattle breeds, his question was what could be done to reduce this. 

Animal welfare was introduced to the congress for the first time. Prof Cathy Dwyer from Scotland’s Rural College presented a session on, ‘Can animal welfare contribute to improved production efficiency?’

The oldest conception of animal welfare is the five freedoms adapted to the five welfare needs of animals, namely a suitable environment, a suitable diet, exhibiting normal behaviour patterns, being with or being apart from other animals, and protection from pain, injury, suffering, and disease. Studies demonstrate that animal welfare can be an important and effective part of production efficiency, and that animal welfare should be seen as an integral component of improving the sustainability of livestock. 

Prof HO de Waal from the Predation Management Centre at the UFS presented a session on the impact of predation on livestock production, with the tile: The need for coordinated predation management in South Africa – quo vadis? He said: “The current approach to predation management is fragmented and uncoordinated. Solutions for the management of human-wildlife conflict require a South African institutional memory. Most of the information on predation and the hunting of predators is held by specialist predator hunters and farmers. In a system of coordinated predation management, farmers and government are equal partners, each with specific responsibilities.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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