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14 May 2019 | Story Thabo Kessah | Photo Tsepo Moeketsi
Prof Ashafa
Prof Ashafa’s research documents plants used by the Basotho in the management of different ailments.
The Phytomedicine and Phytopharmacology Research Programme (PPRP) in the Department of Plant Sciences on the Qwaqwa Campus researches the biological effects of medicinal plants used in the folkloric medicine of the Eastern Free State, particularly to explore the values and contribution of indigenous knowledge systems (IKS) towards broader scientific research. This is according to the programme’s principal investigator and researcher, NRF C2-rated researcher, Professor Anofi Ashafa. 

 “Our research is mainly aimed at documenting plants used by the Basotho in the management of different ailments and to further discover, isolate, and purify active phytoconstituents that are responsible for disease curation or amelioration, thereby assisting in the global promotion of accessible and affordable medication in developing countries,” said Prof Ashafa. 

Since 2012, the PPRP has worked extensively on Basotho medicinal plants (BMP) used as antimicrobials, antioxidants, antidiabetics, antitubercular, anticancer, anthelmintic, and antidiarrheal agents, starting from biological activities up to the  evaluation of the toxicity of these plants for the kidney, liver, and heart functions in order to establish safe dosage parameters. These activities have led to the discovery of four potent antidiabetic biomolecules that are awaiting the processes of patency and commercialisation. Additional outputs include 104 published peer-reviewed articles , 7 postdoctoral fellows, 6 PhDs, 9 master’s, and 16 honours graduates. 

“Our research informs teaching and the development of expertise in ethnobotany, 
phytomedicine, and phytopharmacology in order to contribute to the National Development Plan (NDP) through human capacity development, skills, and knowledge transfer.

The group is also investigating some medicinal plants on the endangered red list of the South African National Biodiversity Institute (SANBI), through micropropagation and field trials as well as proposing conservation strategies to preserve these valuable species.

The PPRP consists of postdoctoral fellows, PhD, master’s, and honours students and research is done in collaboration with several local and international universities as well as the Agricultural Research Council of South Africa. 


News Archive

Tiny microbes may solve large problems of water contamination, says Prof Esta van Heerden
2014-12-08

Small solutions for big problems

According to Prof Esta van Heerden, professor in the Department of Microbial, Biochemical and Food Biotechnology at the University of the Free State (UFS), this might hold some truth in current terms of water treatment strategies for waste and industrial effluents.

“There is little doubt in popular literature that eminent water crises are looming, not only with respect to the supply, but quality and effectiveness of various treatment options as well. The UFS’s Department of Microbial, Biochemical and Food Biotechnology is partnering with the Technology Innovation Agency to evaluate water treatment technologies that are applied worldwide and to extend these new or adapted options to innovative and interested clients in South Africa,” says Prof Van Heerden.

“The research focuses on using extreme microbes to tackle big contaminations and the results are amazing,” says Prof Van Heerden.

These microbes are fast becoming the stars on sites and developing these exciting systems allows for greener treatment options. It is fascinating that they can deal with metals, including chromium and uranium, cyanide, petroleum and diesel.

Of utmost importance is the development of a treatment for acid mine drainage.

“Interests have been overwhelming and thus far partners have allowed pilot scale development on their sites with very promising results. These initiatives are driven by responsible partners who strive to be innovative and develop sustainable technologies for good quality water that can be released in the environment,” Prof Van Heerden says.

The research group has set up a pipeline to serve the water communities’ needs. It provides an accessible toolkit for water analysis. A tailor-made treatment option is also developed and showcased in the laboratories. It has the added benefit that Geosyntec Consultants, USA, will ensure faster roll-out by sharing their vast experience on any related aspects.

 

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