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11 October 2019 | Story Leonie Bolleurs | Photo Supplied
Staff and Students from the Department of Physics
Staff and students from the UFS Department of Physics with parts of the newly arrived astronomical spectrograph for the Boyden Observatory 1,5-m telescope. From the left, are: Dr Pat van Heerden, Daniel Kulik (honours student), Joleen Els (third-year student), Justin Cooper (honours student), Helene Szegedi (lecturer), Professor Petrus Meintjes, Dr Brian van Soelen, and Dr Richard Gray.

Stable atmospheric environments and near perfect weather conditions were the main reasons for the establishment of the Boyden Observatory a few kilometres outside Bloemfontein. This astronomical research observatory and science education centre is managed by the Department of Physics at the University of the Free State (UFS).

With the newly acquired astronomical spectrograph for the Boyden Observatory 1,5-m telescope, scientists will be able to gain visual access to both the Northern and Southern Hemisphere skies.

Collaboration with expert in stellar spectroscopy 


The spectrograph, mainly developed and built by Dr Richard Gray, will be used collaboratively for astronomical research by the UFS and the Appalachian State University (ASU) in North Carolina, where Dr Gray is based. 

Dr Gray is a world-renowned expert in stellar spectroscopy and leading author of one of the most influential textbooks on stellar spectroscopy, Stellar Spectral Classification, with co-author Christopher J Corbally.

Dr Gray recently received a Fulbright Scholarship from the Fulbright Foundation to spend a full year in the UFS Department of Physics, where he will lecture several Astronomy classes and do research in collaboration with personnel of the UFS Astrophysics Research Group. He will also lead the assembly of the instrument over the next few weeks, working with personnel and students in the Department of Physics as well as the UFS Instrumentation Division.

According to Prof Pieter Meintjes, Senior Professor from the UFS Department of Physics, some components of the instrument have been developed and constructed by the university’s Instrumentation Division, with key components purchased from funding by the Directorate: Research Development at the UFS.

Unique capability in infrastructure 

“The availability of a sophisticated instrument of this nature on the 1,5-m telescope will place the UFS Astrophysics Group in an elite bracket in terms of the available infrastructure for astronomical research,” said Prof Meintjes.

He explained: “The combined polarimetric-spectroscopic capability in one single instrument is unique. Combined with the fact that it is hosted on a research instrument that is utilised and maintained exclusively by the UFS Astronomy Group in the Department of Physics, gives this group a competitive edge in relation to most international astronomy groups.” 

The instrument is valued at close to R1,5 million. 

The Boyden Observatory
The Boyden Observatory. (Photo:Supplied)

According to Prof Meintjes, the instrument will be mounted at the backend of the UFS Boyden 1,5-m telescope and will allow them to do simultaneous polarimetry and spectroscopy of astronomical sources. “This is vital for the research we are working on,” he said.

International collaboration and student development

The instrument also brings with it the possibility of forging international collaborations for research as well as student development. “This can advance the stature of the UFS as an internationally respected research-led tertiary institution,” said Prof Meintjes. 

The possibility of making the UFS Boyden 1,5-m telescope completely remote-controlled, is being investigated. “This will serve the observational needs of researchers from both the UFS and the ASU, with researchers at ASU able to access the telescope for their own in-house research programmes. The availability of such an instrument on the UFS 1,5-m telescope also opens up the possibility to accommodate visiting researchers from ASU or elsewhere in the world at Boyden,” said Prof Meintjes.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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