
Some of the guests attending the launch of the research contract are: Dr Siyabulela Ntutela (Deputy Director: Biotechnology at the Department of Science and Technology), Dr Godfrey Netswera (Manager of Thuthuka and the Support Programme at the National Research Foundation (NRF)), Dr Esta van Heerden (Platform Manager and lecturer at the Department of Microbial, Biochemical and Food Biotechnology at the UFS), Mr Butana Mboniswa (Chief Executive Officer of BioPAD), and Mr Vuyisele Phehani (Portfolio Manager for BioPAD). 
Photo: Leonie Bolleurs
The University of the Free State (UFS) has been awarded a massive R13,7 million contract to conduct research into prehistoric micro-organisms which live under extreme conditions, for example in mineshafts.
This is one of the biggest research contracts awarded to the UFS in recent years.
The biotechnology research contract was awarded to the UFS by BioPAD, a South African biotechnology company that brokers partnerships between researchers, entrepreneurs, business, government and other stakeholders to promote innovation and create sustainable biotechnology businesses.
The project is endorsed by the Department of Science and Technology and the National Research Foundation (NRF), which contributes to the bursaries of the 17 postgraduate students on the programme.
The contract involves the establishment of a Platform for Metagenomics -  a technique which allows researchers to extract the DNA from microbes in their natural environment and investigate it in a laboratory. 
“Through this platform we will be able to understand deepmine microbial populations 
and their potential application in the search for life in outer space.  It is most likely 
that, if life were to be found on other planets in our solar system, it would probably 
resemble that which existed millions of years ago on earth.  Apart from all this, these 
organisms have unique properties one can exploit in biotechnological application for 
South Africa and its community,” said Dr Esta van Heerden, platform manager and 
lecturer at the UFS Department of Microbial, Biochemical and Food Biotechnology. 
She is assisted by her collegues, Prof. Derek Litthauer and Dr Lizelle Piater.
“The platform aims to tap into the unique genetic material in South African mines 
which will lead to the discovery of new genes and their products.  These new and unique products will find application in the medical field (anti-cancer, anti-bacterial en anti-viral cures), the industrial sector (nanotechnology, commercial washing agents and the food industry), environmental sector (pollution management, demolition of harmful metals and other toxic waste),” said Dr Van Heerden.
According to Dr Van Heerden, the Metagenomics Platforms stems from the Life in 
Extreme Environments (LExEN) programme which was started in 1994 by Princeton 
University in the United States of America (USA) in South African mines with grants 
from among others the National Aeronautics and Space Administration (NASA) and 
the National Science Foundation (NSF) in the USA.  Other international collaborators 
on the project include Geosynec Consultants Inc. (USA), Oak Ridge National 
Laboratory (USA), the University of Tennessee (USA) and in South Africa the 
Universities of the Witwatersrand, North West and Limpopo and companies like BHP 
Billiton, MINTEK and mining companies like Harmony, Gold Fields and AngloGold 
Ashanti.
The research field laboratory of the Metagenomics Platform, which was situated in 
Glen Harvey, was moved to the Main Campus of the UFS in Bloemfontein.  “In this 
way the university has become the central hub for all research programmes.  We are 
also the liaison between the LExEN programme and the various mining companies 
involved,” said Dr Van Heerden.  The new laboratory was introduced during the 
launch of the research contract.
“Our decision to commit BioPAD to this project stems from the company’s commitment to advance human capacity development to strengthen South Africa’s research infrastructure.  It is also part of our aim to create and protect intellectual property,” said Mr Butana Mboniswa, Chief Executive Officer of BioPAD.
Talking on behalf of the UFS senior management, Prof. Teuns Verschoor, Vice-Rector 
of Academic Operations, said that the university shares the excitement to be part of 
the exploration of unknown forms of life, the discovery of new genes and 
their products and in applying newly gained knowledge to better understand our 
universe.
Media release 
Issued by: Lacea Loader 
Assistant Director: Media Liaison  
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za
27 March 2007