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04 June 2019 | Story Valentino Ndaba | Photo Charl Devenish
Prof Cathryn Tonne
Air pollution not only costs lives, it costs money too. Pictured is Prof Cathryn Tonne presenting a guest lecture on air pollution at the Bloemfontein Campus.

Health effects associated with ambient air pollution (AAP) have been well documented. Subsequently, the relationship between pollution and financial outcomes have also become a focus for case studies globally. An Environmental Research journal article revealed that “low and middle-income countries are disproportionately affected by the global burden of adverse health effects caused by AAP”. 

A high price to pay

In 2012, high concentrations of air pollution caused 7.4% of all deaths, costing South Africa up to 6% of its Gross Domestic Product. According to the recent International Growth Centre study conducted by senior University of Cape Town researchers, this is a direct consequence of the country’s heavy dependence of fossil fuels, a source of health-damaging air pollution and greenhouse pollutants.

Stunted human and economic growth

These South African statistics are attested to by Prof Cathryn Tonne who recently presented a guest lecture on air pollution which was hosted by the University of the Free State (UFS) Business School.

“Air pollution can affect economic development through several pathways, and health is an important one. Air pollution is linked to shorter life expectancy, chronic disease, asthma exacerbation and many other health outcomes that result in absenteeism from work and school. These have large direct costs to the health system.” 

Prof Tonne says that air pollution exposure in children is linked to reduced cognitive development, with important impacts on human capital. As a result, children are not reaching their full potential in terms of neurodevelopment, which has an effect on their income prospects and the economy as a whole. 

Resolving a looming disaster

Technology may be employed to radically clean the air. Cities need to lead in the reduction of air pollution by promoting renewable energy, using active transport such as walking or cycling, and investing in infrastructure to make this safe and attractive. 

With researchers playing a major role in strengthening the case for aggressive air pollution control, the government needs to implement policies in order to control sources of air pollution. This global health and economic issue also requires individuals and communities to play their part to improve air quality.

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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