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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Scientists discover a water reservoir beneath the Free State

2009-12-09

Dr Holger Sommer

The Mantle Research Group Bloemfontein (MRGB), under the leadership of Dr Holger Sommer, a senior lecturer in the Department of Geology at the University of the Free State (UFS), has discovered an enormous water reservoir 160 km beneath the Free State.

This discovery, according to Dr Sommer, is the first of its kind in South Africa after he had previously made a similar finding in Colorado, USA.

However, this water cannot be used for human consumption. “It is not frozen water; it is not molecular water; it is not fresh water; it is not salty water; it is OH – water which is sitting in the crystal lattice,” he said.

He said the reservoir was comparable in size to Lake Victoria in Tanzania.
The researchers collected eclogites from the Roberts Victor (Rovic) Mine close to the town of Boshof, south-west of the Free State, for their study.

“The Rovic eclogites are rocks which represent former oceanic crust transported into the earth’s interior by complex plate tectonic processes about 2.0 billion years ago,” explained Dr Sommer.

“These rocks were finally carried back to the earth’s surface by volcanic (kimberlite) eruptions around 130 million years ago. Eclogitic rocks are therefore a window into the Earth’s interior.”

The question from the beginning for all MRGB scientists was: Is there water inside these rocks in such depth, and if so, where is it located?

To answer this question, Dr Sommer and his research fellows separated single mineral grains from eclogite samples and prepared about 100 micrometer (0,1 mm) thick rock sections. Afterwards, specific particle accelerator (Synchrotron) measurements were carried out in the city of Karlsruhe in Germany.

“And indeed, the MRGB found water inside the studied rocks from the Roberts Victor Mine,” he said. “The water was located in defect structures in crystal lattices and along boundaries between single mineral grains.”

“The occurrence of water at such depth would give first evidence that all water of the oceans could be stored five to ten times in the earth’s mantle.”
The study was conducted about a year ago.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za
4 December 2009

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