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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Chemistry gets substantial grants

2013-06-10

At the experimental setup of the high temperature reduction oven for research in heterogeneous catalysis are, front from left: Maretha Serdyn (MNS Cluster prestige PhD bursar), Nceba Magqi (Sasol employee busy with his MSc in Chemistry) and Dr Alice Brink (Formal MNS Cluster postdoctoral fellow and lecturer in Inorganic Chemistry); back Profs Jannie Swarts (Head: Physical Chemistry), André Roodt, and Ben Bezuidenhoudt (Sasol Professor in Organic and Process Chemistry).
10 June 2013

Three research groups in the Department of Chemistry received substantial grants to the value of R4,55 million. The funding includes bursaries for students and post-doctoral fellows, mobility grants, running costs and equipment support, as well as dedicated funds for two young scientists in the UFS Prestige Scholar Programme, Drs Lizette Erasmus and Alice Brink.

The funding comes from Sasol, the THRIP programme of the National Research Foundation (NRF) and PetLabs Pharmaceuticals for the overarching thrust in Organic Synthesis, Homogeneous and Heterogeneous Catalysis. The programme has a broad focuse on different fundamental and applied aspects of process chemistry. Research groups of Profs Andreas Roodt (Inorganic), Jannie Swarts (Physical) and Ben Bezuidenhoudt (Organic / Process), principal members of the focus area of (Green) Petrochemicals in the Materials and Nanosciences Strategic Research Cluster (MNS Cluster) will benefit from the grant.

This funding was granted based on the continued and high-level outputs by the groups, which resulted in more than 40 papers featuring in international chemistry publications in merely the past year. A few papers also appeared in the top experimental inorganic chemistry journal from the American Chemical Society, Inorganic Chemistry. These high-impact papers address important issues in catalysis under the UFS Material and Nanosciences Research Cluster initiative, as well as other aspects of fundamental chemistry, but with an applied approach and focus.

Prof Andreas Roodt, Distinguished Professor and Chairperson of the Department of Chemistry, said the grants will enable the three research groups to move forward in their respective research areas associated with petrochemicals and other projects, and enable additional students in the department to benefit from it. It will also ensure that these groups can continue and maintain their research on different molecular and nano-scale materials. Current experiments include conversions under extremely high gas pressures (typical 100 times that in motor car tyres). This takes place at the molecular level and at preselected nano-surfaces, to convert cheaper feed-stream starting materials into higher value-added products for use as special additives in gasoline and other speciality chemicals.

The funding support forms part of the Hub-and-Spoke initiative at Sasol under which certain universities and specifically the UFS Department of Chemistry have been identified for strategic support for research and development. The department and the UFS gratefully acknowledge this continued and generous support from all parties concerned.

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