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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Traditional medicine can play important role in modern drugs discovery

2014-11-11

Indigenous knowledge possesses a great potential to improve science. Making use of this source may lead to advanced technological innovations. This is according to Dr Sechaba Bareetseng, UFS alumnus and Indigenous Knowledge Systems (IKS) Manager at the Council for Scientific and Industrial Research (CSIR).
Dr Bareetseng recently addressed the seventh annual IKS symposium on the Qwaqwa Campus.
“Interfacing indigenous and local knowledge with scientific knowledge has the potential of encouraging and developing inventions, especially in the pharmaceutical industry,” said Dr Bareetseng.

“Such interfacing can also enable access to both sets of knowledge without any discrimination whatsoever. It would also encourage co-existence that would improve understanding between the two.”

“Traditional medicine,” said Dr Bareetseng, “can play an extended role in modern drugs discovery as it is already happening in Botswana and New Zealand. These two countries are leading this wave of new thinking in as far as drug development is concerned.”

Dr Bareetseng also called on established researchers to start embracing the local communities into their research.

“Contemporary scientific research demands that local communities must co-author research conducted within and with them by the universities and research institutions. This would help in maintaining trust between the researchers and the communities that feel exploited. Regular feedback would also make communities feel part of the developments,” Dr Bareetseng argued.

He further called on the pharmaceutical companies specifically and researchers in general to convert valuable indigenous knowledge and resources into products and services of commercial value. “Plants, the ecosystem and indigenous knowledge must be preserved to provide a source of income for the local communities. Communities must also be protected from foreign exploitation of their intellectual property.”

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