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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

CDS receives another international grant from the NIH

2015-12-11

Dr Carla Sharp

The Centre for Development Support (CDS) is partner to another international research grant from the National Institutes of Health (NIH) in the United States. The new project follows an earlier project funded by the NIH, which focused on the mental health of orphans and vulnerable children.

The new project is to focus on investigating possible improvements in the mental health and cognitive development of orphaned and vulnerable children aged between seven and eleven years, by means of improved community-based care in the Mangaung Township area in Bloemfontein. The project will stretch over three years and has a budget of approximately R10 million.

“We shall use the Mediational Intervention of Sensitizing Caregivers (MISC) approach and it will be applied by community-based organisations,” says Dr Deidre van Rooyen, Acting Director of the CDS.

MISC applied by caregivers has produced good results elsewhere in the world. “This is the first time MISC will be tested by community-based organisations,” says Prof Lochner Marais of the CDS, who is also the principal investigator in South Africa.

“In addition to working with four community-based organisations in Mangaung, Childline Free State will also be actively involved in the project,” Marais added.

The project is being conducted in collaboration with Dr Carla Sharp as principal investigator at the University of Houston, and Prof Michael Boivin (an international expert on MISC) at the Michigan State University. Dr Sharp was recently appointed visiting professor at the CDS.

“It is indeed a great privilege to be working with the CDS on yet another project,” Dr Sharp remarked, also noting that “the project is preliminary in nature and could evolve into a much bigger research project in future”.

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