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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Plant eco-physiologist finds effective solutions for crop optimisation

2016-07-24

The bio-stimulant was tested on
this citrus. This is the first time
that the product has been tested
on a crop.

In a time characterised by society facing increasing population growth, food crises, and extreme climatic conditions such as drought, it is essential for farmers to integrate science with their work practices in order to optimise crops.

Role of photosynthesis and plant sap data

By knowing how to use photosynthesis and plant sap data for determining plant health, fast and effective solutions could be established for the optimisation of crops. This technique, which could help farmers utilise every bit of usable land effectively, is the focus of Marguerite Westcott’s PhD study. She is a junior lecturer and plant eco-physiologist in die Department of Plant Sciences at the University of the Free State.

Westcott uses this technique in her studies to prove that a newly-developed bio-stimulant stimulates plants in order to metabolise water and other nutrients better, yielding increased crops as a result.

Agricultural and mining sectors benefit from research

The greatest part of these projects focuses on the agricultural sector. Westcott and a colleague, Dr Gert Marais, are researching the physiology of pecan and citrus trees in order to optimise the growth of these crops, thus minimising disease through biological methods. Field trials are being conducted in actively-producing orchards in the Hartswater and Patensie areas in conjunction with the South African Pecan Nut Producers Association (SAPPA) amongst others.

The principles that Westcott applies in her research are also used in combination with the bio-stimulant in other studies on disturbed soil, such as mine-dump material, for establishing plants in areas where they would not grow normally. This is an economical way for both the agricultural and mining sectors to improve nutrient absorption, stimulate growth, and contribute to the sustainable utilisation of the soil.

The bio-stimulant contributes to the immunity of the plants.
It was tested in these pecan nut orchards (Hartswater).

Soil rehabilitation key aspect in research projects

“One of two things is happening in my research projects. Either the soil is rehabilitated to bring about the optimal growth of a plant, or the plants are used to rehabilitate the soil,” says Westcott.

Data surveys for her PhD studies began in 2015. “This will be a long-term project in which seasonal data will be collected continuously. The first set of complete field data, together with pot trial data, will be completed after the current crop harvest,” says Westcott.

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