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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Maize breeder rewarded for his research to enhance food security in Africa

2016-08-26

Description: Maize breeder rewarded Tags: Maize breeder rewarded

Prof Maryke Labuschagne from the UFS Department
of Plant Sciences, Berhanu Tadesse Ertiro, a
postgraduate student in Plant breeding at the UFS,
and Dr Peg Redinbaugh of the US Department of
Agriculture in Wooster, Ohio.
Photo: Supplied

Ethiopia is one of the African countries, deeply affected by food insecurity. Berhanu Tadesse Ertiro, a citizen from Ethiopia started his career - after graduating with his undergraduate degree in 2003 - as a junior maize breeder. Today he is pursuing his doctorate degree in Plant Breeding at the University of the Free State (UFS).

His research had made some great strides in contributing to food security in Africa. He recently received a fellowship from the prestigious Norman E. Borlaug Leadership Enhancement in Agriculture Program (Borlaug LEAP).

This fellowship is only awarded to students whose research has relevance to the national development of the student’s home country or region. The aim of these fellowships are to enhance the quality of thesis research of graduate students from developing countries who show strong promise as leaders in the field of agriculture and related disciplines.

Low soil fertility a major maize production constraint
Berhanu is also a visiting student at the International Maize and Wheat Improvement Center (CIMMYT) in Kenya, where he is running field experiments for his PhD thesis dissertation. His research focuses on Nitrogen Use Efficiency (NUE) and Maize Lethal Necrosis (MLN) disease tolerance. Low soil fertility and MLN are among the major maize production constraints in eastern and southern Africa, where maize is staple food.

Such hybrids have the potential to contribute greatly
towards food security among farmers and their
families through increased productivity.

The use of new tools could increase breeding efficiency and reduce the time needed for the release of new stress tolerant hybrids. Such hybrids have the potential to contribute greatly towards food security among farmers and their families through increased productivity. Berhanu is looking at the feasibility of genome wide selection for improvement of NUE in tropical maize.

Fellowship includes mentorship and supervision across borders
The programme supports engaging a mentor at a United States university and Consortium of International Agricultural Research Centers (CGIAR). During his fellowship, he will be supervised and mentored by Prof Maryke Labuschagne of the UFS, Prof Rex Bernando, a professor of Corn Breeding and Genetics at the University of Minnesota and Dr Biswanath Das of CIMMYT, Kenya.

As a LEAP fellow, Berhanu was invited to attend the 30th Annual World Food Prize events to take place in October 2016, in Des Moines, Iowa. The week will include his attendance at the Board for International Food and Agricultural Development meeting, participation at side-events at the Borlaug Dialogue International Symposium and the World Food Prize.

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