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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Groundwater management vital for groundwater sustainability

2016-11-09

Description: Dr Yolanda Kotzé Tags: Dr Yolanda Kotzé

Dr Yolanda Kotzé, Affiliated Researcher in the
UFS Institute for Groundwater Studies, is passionate
about the management of groundwater.
Photo: Rulanzen Martin

An interest in groundwater resource management ignited the spark for a PhD research thesis by Dr Yolanda Kotzé, Affiliated Researcher in the Institute for Groundwater Studies (IGS) at the University of the Free State (UFS).

Her PhD research thesis titled, A Framework for Groundwater Use Authorisations as Part of Groundwater Governance in Water Scarce Areas within South Africa, was the result of her interest in groundwater resource management. Dr Kotzé identified the agricultural sector as one of the major water users, and a decision was made to conduct research within this sector.

Research funded by Institute for Groundwater Studies
Groundwater is water found underground in cracks and spaces in soil, sand, and rocks. It is stored in, and moves slowly through geological formations of soil, sand, and rocks (aquifers). The National Department of Water and Sanitation was indirectly the client for this research. The research project was funded by the IGS. Given the current drought, effective groundwater resource management can be achieved within all sectors through sustainable abstraction and use without over-abstraction.

“Groundwater can be effectively managed
in the agricultural sector by sustainable use,
monitoring the quantity of groundwater use,
and measuring groundwater levels,”
said Dr Kotzé.

Research addresses improvement of groundwater management
Her promotor, mentor, teacher, and friend, the late Prof Gerrit van Tonder, introduced her to the field of Geohydrology, and especially to groundwater resource management. “With my research, I made a significant contribution to the improvement of groundwater governance and groundwater resource management, as well as to the handling of groundwater use authorisations for irrigation purposes in South Africa,” said Dr Kotzé. With this significant contribution, she attempts to address the phenomenon of poor groundwater allocation and groundwater resource management by means of a framework. The development of this framework has shown the value of action research in an attempt to find a solution to a problem. “Groundwater can be effectively managed in the agricultural sector by sustainable use, monitoring the quantity of groundwater use, and measuring groundwater levels,” said Dr Kotzé.

The methodology of the research consisted primarily of action research, which has a five-phase cyclical process. The research was Dr Kotzé’s application for a PhD in Geohydrology at the UFS in 2012. The research was completed in 2015.

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