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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

Researcher wins prize for her work to reduce environmental pollution

2016-12-26

Prof Danie Vermeulen, Dean of the Faculty of Natural
and Agricultural Sciences, and Josepha Zielke, a
PhD student at the Institute for Groundwater studies at the
University of the Free State.
Photo: Leonie Bolleurs

Josepha Zielke, a PhD student at the Institute for Groundwater Studies at the University of the Free State (UFS), received the prize for the best student presentation at the International Mine Water Association (IMWA) symposium in Leipzig, Germany, this year. Her paper was titled Fine Ash Leaching in Tailings Dams – An Impact on the Underlying Aquifers?

Zielke said: “It is an honour to receive this prize as a student. IMWA is a big association which allows you to establish a network with other scientists, to exchange opinions and ideas and to gain new inspiration for your own work. It was exciting and informative to hear about the research conducted around the world and to meet the researchers themselves.”

Born in Germany, Zielke always wanted to study overseas. During an exchange year in Grade 11, she visited South Africa. When she had to make a decision about in which country to complete her studies, South Africa was first choice as she was familiar with the people and the country.

Zielke joins leading institute on groundwater research in the country
She completed her BSc Hons in Geology at the Nelson Mandela Metropolitan University. After working for a year in exploration, she decided to focus her studies on water-related problems which has been a growing issue, not only in South Africa, but in many places around the world. Zielke heard that the UFS Institute for Groundwater Studies was the leading institute on groundwater research in the country, and decided to join the university.

After completing her MSc research, An analysis of the geochemical weathering profile within a fine ash tailings dam, Mpumalanga, South Africa, Zielke started the research for her PhD project on groundwater pollution along a fault system in Mpumalanga.

Research adding value to the environment by reducing pollution
She explains the focus of her research: “Several production plants and mine waste facilities are located on or near these geological structures which could be a possible cause of ground and surface water pollution. With the aid of geophysical ground surveys (using electromagnetics and electrical resistivity tomography), aquifer and tracer tests, we are trying to determine where the pollution is coming from, how far it has been distributed and to model the potential risks.

“This research will add value to the environment by preventing or at least reducing pollution leaking into the environment. Industrial sites always have a negative footprint on the environment but at least we try and contain it by finding the cause of ground and surface water pollution. Thereafter we try and solve the pollution problem or at least mitigate the damage to prevent the spreading of ground and surface water pollution in the area.”

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