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Fighting COVID-19: Here is how we are helping

16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish

Farmovs — In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19.

The trial is expected to include more than 45 countries worldwide, including a number of South African sites.

Farmovs
FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients.

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe. FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.

News Archive

From music to theology: Stats Unit valuable in research process

2017-02-23

Description: Prof Robert Schall Tags: Prof Robert Schall

Prof Schall, head of the UFS Statistical Consultation Unit
Photo: Leonie Bolleurs

Whether it is analysing data on church attendance, climate change in the Northern Cape or injuries among elite female hockey players, the Statistical Consultation Unit at the University of the Free State (UFS) can assist researchers from the planning of research to publication therof.

Many students and researchers think that the time to consult a statistician is after their research data has been collected. According to Prof Robert Schall, head of the unit, the most significant contribution a statistician can make to a research project is often during its planning. Preferably all researchers should consult the unit early in the research process.

Statistical consultation service free for postgraduates
The consultation unit, established in 2014 in the Department of Mathematical Statistics and Actuarial Science, provides support to all UFS researchers. This service is rendered to postgraduate students at no charge.

“The unit can make a contribution throughout the research process, from the planning of the research project, through the analysis of research data, up to the publication of the findings. I have been involved in projects where, for example, a few very simple changes to the design of a questionnaire would have saved the researcher and the statistician a lot of trouble. It will be beneficial for researchers to have their questionnaires and study proposals (where relevant), reviewed by a statistician,” Prof Schall said.

“The unit can make a contribution
throughout the research process,
from the planning of the research
project, through the analysis of
research data, up to the publication
of the findings.”

Fascinating research topics deliver fascinating data
The professor assisted in a study for the Department of Soil, Crop and Climate Sciences to determine whether rainfall in the Northern Cape had changed over the past 90 years, potentially indicating climate change.

Other interesting projects he has worked on came from the Department of Exercise and Sport Sciences. “Who will not be fascinated by data sets on aspects of rugby, cricket or even netball? One significant finding was a predictor of injury in elite female hockey players. The PhD student identified a pre-season test which predicted the occurrence of an in-season injury with 100% specificity and 100% sensitivity. The finding was quite surprising, and, if the results can be replicated, obviously would be useful in the prevention of injuries,” he said.

This is, of course, not an exhaustive list of projects the unit has worked on. “Not in my wildest dreams would I have expected to be involved in projects coming from the Faculty of Theology, or from the Odeion School of Music,” Prof Schall said.

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