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16 April 2020 | Story Department of Communication and Marketing | Photo Charl Devenish
Farmovs
In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.

The University of the Free State (UFS) is committed to supporting government’s efforts to overcome the COVID-19 pandemic. During this challenging time, dedicated staff members at the UFS continue to provide services as a testimony to their commitment to advance public knowledge of COVID-19 for the greater good of South Africa.

The following is a synopsis of the areas in which the UFS is actively assisting.

Public Health Emergency Solidarity Trial
Clinicians from the Department of Internal Medicine, the Department of Critical Care, and the Division of Virology will be working with FARMOVS to participate in the Public Health Emergency Solidarity Trial initiated by the World Health Organization (WHO). This international randomised trial will evaluate four treatment options (remdesivir, lopinavir/ritonavir, lopinavir/ritonavir plus interferon, chloroquine or hydroxychloroquine) for the treatment of COVID-19. 

The trial is expected to include more than 45 countries worldwide, including a number of South African sites. 

Farmovs

FARMOVS is in a planning process to support all the Bloemfontein hospitals, including Pelonomi, Universitas, 3 Military Hospital, Mediclinic, and Rosepark, in conducting the largest global trial on COVID-19 – the Public Health Emergency Solidarity Trial, under leadership of the WHO.   

Negotiations are ongoing between the UFS and the Department of Health in the Free State for FARMOVS to offer support with the continuation of healthcare to non-COVID-19 patients in an attempt to free up space at Universitas Hospital for isolation of COVID-19 patients. 

In 2019, FARMOVS was pre-qualified by the WHO to support clinical studies aimed at improving access to quality generic medicines across the globe.  FARMOVS also receives feasibility requests for support with the evaluation of existing drugs (repurposing) as well as the development of novel drugs for the treatment of COVID-19 – this is an ongoing process.

Disaster Management Training and Education Centre (DiMTEC)
DiMTEC represents the UFS on the Provincial Joint Operation Centre (PROVJOC). The PROVJOC is a fully equipped, dedicated facility that is proactively established to enable all relevant role players /disciplines to jointly manage all safety and security-related aspects of any planned event or any major incident which has occurred or is imminent – especially in the response and recovery operations phase – at the strategic and/or tactical level, using the Unified Command System. This facility is also linked to all other established safety and security centres.

Research and Innovation
The UFS hosts a SARChI Research Chair in vector-borne and zoonotic diseases, and recently invested in the establishment of a biosafety level-3 facility. Hence, there is expertise on the campus to plan and conduct research on zoonotic and medically significant viruses. In addition, there are research groups focusing on protein expression systems with potential for utilisation in the development of diagnostic assays with application in either diagnosis or surveillance.

Currently, researchers at the UFS have established several projects that will contribute directly towards the COVID-19 outbreak.


News Archive

Water erosion research help determine future of dams
2017-03-07

Description: Dr Jay le Roux Tags: Dr Jay le Roux

Dr Jay le Roux, one of 31 new NRF-rated
researchers at the University of the Free State,
aims for a higher rating from the NRF.
Photo: Rulanzen Martin

“This rating will motivate me to do more research, to improve outcomes, and to aim for a higher C-rating.” This was the response of Dr Jay le Roux, who was recently graded as an Y2-rated researcher by the National Research Foundation (NRF).

Dr Le Roux, senior lecturer in the Department of Geography at the University of the Free State (UFS), is one of 31 new NRF-rated researchers at the UFS. “This grading will make it possible to focus on more specific research during field research and to come in contact with other experts. Researchers are graded on their potential or contribution in their respective fields,” he said.

Research assess different techniques
His research on water erosion risk in South Africa (SA) is a methodological framework with three hierarchal levels presented. It was done in collaboration with the University of Pretoria (UP), Water Research Commission, Department of Agriculture, Forestry and Fisheries, and recently Rhodes University and the Department of Environmental Affairs. Dr Le Roux was registered for 5 years at UP, while working full-time for the Agricultural Research Council – Institute for Soil, Climate and Water (ARC-ISCW).

Water erosion risk assessment in South Africa: towards a methodological framework
, illustrates the most feasible erosion assessment techniques and input datasets that can be used to map water erosion features in SA. It also emphasises the simplicity required for application at a regional scale, with proper incorporation of the most important erosion-causal factors.

The main feature that distinguishes this approach from previous studies is the fact that this study interprets erosion features as individual sediment sources. Modelling the sediment yield contribution from gully erosion (also known as dongas) with emphasis on connectivity and sediment transport, can be considered as an important step towards the assessment of sediment produce at regional scale. 
 
Dams a pivotal element in river networks

Soil is an important, but limited natural resource in SA. Soil erosion not only involves loss of fertile topsoil and reduction of soil productivity, but is also coupled with serious off-site impacts related to increased mobilisation of sediment and delivery to rivers.

The siltation of dams is a big problem in SA, especially dams that are located in eroded catchment areas. Dr Le Roux recently developed a model to assess sediment yield contribution from gully erosion at a large catchment scale. “The Mzimvubu River Catchment is the only large river network in SA on record without a dam.” The flow and sediment yield in the catchment made it possible to estimate dam life expectancies on between 43 and 55 years for future dams in the area.
 
Future model to assess soil erosion
“I plan to finalise a soil erosion model that will determine the sediment yield of gully erosion on a bigger scale.” It will be useful to determine the lifespan of dams where gully erosion is a big problem. Two of his PhD students are currently working on project proposals to assess soil erosion with the help of remote sensing techniques.

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