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21 December 2020 | Story Andre Damons | Photo Supplied
The research team helps a giraffe to get up after they have finished collecting data.

Researchers from the University of the Free State (UFS) hope their research to investigate why some animals prefer or avoid some habitats, will also create awareness for the plight of giraffes which have lost more than 80% of some of their subspecies in East Africa and are facing extinction in the wild.

Dr Marietjie Schutte-Smith, Senior Lecturer in the Department of Chemistry, says the collaborative research being done in South Africa is very unique and could help save subspecies from the brink of extinction – as South Africa has managed to double its giraffe numbers whilst subspecies have declined tremendously.

Why some animals prefer or avoid some habitats

“By using modern analysis techniques and instruments (such as drones and GPS devices), it is possible to study complex environments on a spatial ecology scale and has created the opportunity to investigate why some animals prefer or avoid some habitats,” explains wildlife expert Dr Francois Deacon.

“This in turn opened the door to explore geographic, soil and nutritional qualities the giraffe might prefer or avoid. This is one of the main reasons we are exploring the different factors and driving forces behind a large herbivore’s habitat selection, well-being, body condition parameters and physiological adaptations,” Dr Deacon says.

Veld conditions, plant species composition, tree densities and other available resources such as production yield and water quality determine reproduction successes and how animals disperse, move and distribute over an area. Spatial and ecological distributions of giraffe specifically depend on habitat resources and qualities that in turn affect their complex behavioral tactics and survival.

Strange habits

The research was started back in 2010 by Dr Deacon and Prof Nico Smit from the Department of Animal, Wildlife and Grassland Sciences at the UFS with the pioneering of GPS devices to investigate giraffe spatial ecology and habitat use. The current study was initiated as to why the giraffe would utilise one area more than the other, even if the two habitats had the same tree species, says Dr Schutte-Smith.

Dr Deacon contacted Prof Hendrik Visser and Dr Schutte-Smith from the Department of Chemistry for a possible collaborative effort. Ms Jeaneme Kuhn started her MSc research degree on this project in January 2019 and completed her degree in August 2020 with distinction.

Dr Schutte-Smith says from research done at Rooipoort Nature Reserve it was found that a certain group of giraffes had the strange habit of only eating from specific trees, avoiding similar trees a few metres away. “We wanted to see if this behaviour was due to chemical influences, i.e. if there are specific minerals that are possibly in excess at some places which they avoid, especially since there are mines close by.”

Aim of the research

The main aim of this MSc Chemistry degree, according to Dr Schutte-Smith, is to validate an analytical method for testing leaves and soil samples, using IPC, to see if heavy metals (in excess) are present in the soil, leaves and water and whether this has an influence on the browsing pattern of the giraffes. “Then as secondary aims (for the collaborative effort) we would like to investigate if the giraffe can select one area above the other (core home ranges), to understand what the qualities are that they would select for in the preferred area and what the qualities they avoid are in the other. And lastly to understand what the minimum requirements are to keep the animals happy and healthy, but also to investigate how they search for these qualities,” says Dr Schutte-Smith.

Giraffe conservation

Besides creating awareness of the plight of giraffes, the researchers also aim to create a model for conservation via research and education to be used as an example for other countries. This model incorporates students, academia, professionals, sponsors and stakeholders that cover various topics relating to giraffe education, management and conservation.

They would also like to see the UFS as the institution that has contributed the most to giraffe conservation strategies in Africa by being the leading university in the collection and analysis of information about giraffes and their habitats, increasing conservation education awareness about giraffes and African biodiversity and to develop national and/or regional plans aimed at giraffe conservation.

The research team successfully applied for funding which they used for chemicals and solvents to perform testing as well as sampling.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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