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10 June 2020 | Story Leonie Bolleurs | Photo Supplied
Dr Ehlers was appointed to serve on the National Forensic Oversight and Ethics Board of 10 members for a second term, based on her knowledge in the field of forensic sciences.

Dr Karen Ehlers from the Department of Genetics at the University of the Free State (UFS) was elected as a member of the National Forensic Oversight and Ethics Board (NFOEB) for a second term.

Dr Ehlers has been appointed to the board of 10 members based on her knowledge in the field of forensic sciences. She is currently conducting research focusing on the forensic application of Y-STR markers, the statistical analysis of DNA profiles, and touch DNA.

Making valuable contributions
Her expertise in the field of forensic genetics assists the board – which also handles complaints about alleged violations relating to the abuse of DNA samples and forensic DNA profiles – to oversee the operations of the Forensic Science Laboratory and the National Forensic DNA Database (NFDD). 

“The knowledge I gained from my current research at the UFS has enabled me to make valuable contributions to the board and its recommendations to the Minister of Police,” says Dr Ehlers. 

In her first term as member of the Board – following regular tracking and analysis of reports, the Board noted an increase in the number of outstanding forensic investigative leads – (hits on the National Forensic DNA Database) that were not followed up.

“After we made enquiries, it was determined that the provincial task teams that were to follow up on the leads, were ad hoc structures that lacked the necessary resources. The Board addressed this shortfall by engaging with various stakeholders and helping to establish permanent structures, called Forensic Investigative Units, with dedicated resources – both human and material – to effectively follow up on all forensic DNA investigative leads. The finalised Regulations were published for comment in the Government Gazette on 27 March 2020,” says Dr Ehlers.

Lowering SA crime rate
While serving on this board, she is ensuring that South Africa has a functioning DNA database that contributes to lowering the crime rate in the country. “As a member of the board, I hope to add value to its functioning. I feel that in the future, science will play an even bigger role in crime prevention, detection, and the solving of crimes,” she states.

Dr Ehlers is Programme Director of the Forensic Sciences Programme in the Department of Genetics. She teaches the Crime Scene Management module to second-year students and supervises seven honours, five MSc, and three PhD students. 

Besides her appointment as member of the NFOEB, she values the work she is doing with her students. “The highlight of my career was when my first group of BScHons students in Forensic Genetics graduated and were shortly thereafter appointed by the Forensic Sciences Laboratory as DNA analysts,” she says. 

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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