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25 May 2020 | Story Dr Ralph Clark | Photo Charl Devenish
Afromontane research area in the Eastern Free State.

Africa could be called ‘the continent of mountain archipelagos’ for the unusual fact that most of Africa's mountains are isolated ‘islands’ rather than linear, continuous mountain systems such as those in Asia (e.g. the Himalayas), Europe (e.g. the Alps), and the Americas (e.g. Rockies and Andes). Even in Southern Africa, where we have the linear Great Escarpment (5 000 km long), this system is so old that it has been breached in innumerable places by erosion into a series of independent mountain blocks.

The result of this mountain disconnection is that Africa's mountains display biodiversity patterns more akin to islands than to mountains: rich, exciting, and unique, and full of very localised and interesting species. Likewise, mountain communities have established and evolved unique cultural ways of life and traditions in their particular mountains – isolated from other groups on other mountains. But in some mountains, internecine warfare and tribal conflict caused mountains to become boundaries rather than welcoming places. This was certainly the case during the Mfecane in Southern Africa, ultimately leading to the birth of Lesotho as the ‘Mountain Kingdom’. Colonialism took this to a new level, and – for most of Africa – mountains became international borders between empires, splitting ethnic groups into several nationalities and marginalising large segments of the population in these new countries. This same geopolitical situation continues today, with major implications for the sustainable management of mountain ecosystem services, natural capital, and socio-cultural sustainability in multinational contexts.

The Afromontane Research Unit (ARU) – a continental leader in African mountain research – seeks to explore these socio-ecological complexities in terms of sustainable development, providing research that can help to secure a positive future for the people, biodiversity, and goods and services provided by Africa's mountains. As part of its mission, the ARU is leading the way in encouraging a multidisciplinary community of practice that will drive a science-policy-action interface for Southern African mountains in decades to come. As virtually all of Africa's water comes from its mountains, this is a critical service to a region increasingly at risk from drought and the socio-political implications of rivers and taps running dry. 

Although the Qwaqwa Campus is the home of the ARU, the ARU is welcoming affiliations from across the UFS and beyond. Should you wish to become affiliated to the ARU, please contact the Director, Dr Ralph Clark at ClarkVR@ufs.ac.za. Visit the new ARU's website 

News Archive

Heart-valve studies receive international recognition
2017-07-11

 Description: Heart-valve studies  Tags: Heart-valve studies  

Prof Francis Smit, Head of the Department of
Cardiothoracic Surgery at the UFS, and Manager of the
Robert WM Frater Cardiovascular Research Centre, with
Kyle Davis, Mechanical Engineer at the centre.

Photo: Rulanzen Martin

Three heart-valve studies which have been developed at the Robert WM Frater Cardiovascular Research Centre at the School of Medicine at the University of the Free State (UFS) were recently presented in Monte Carlo at the conference of the prestigious global Heart Valve Society (HVS).

These studies are all headed by Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS, and Manager of the Robert WM Frater Cardiovascular Research Centre.
Prof Smit says the HVS is a combination of the former heart-valve societies of Europe and the US. “Studies on heart-valve disease, heart-valve-related products and operations, as well as the design and development of new valves were presented. There are both clinical and development divisions.

He says the study in which the hemodynamics of their redesigned mechanical poppet valve was compared to a commercial bi-leaflet mechanical heart valve, was named as the best poster presentation in the experimental valve development and numerical flow dynamics division. The study, which was presented by Kyle Davis, mechanical engineer at the centre, competed against some of the best heart-valve research units in the world.

The redesigned valve, based on the 1960s Cape Town poppet valve, has the potential to provide a low-cost solution for mechanical heart-valve replacement. It is possible to produce the titanium ring with 3-D printers and is, together with the silicon poppet valve, extremely inexpensive compared to current mechanical valve-manufacturing processes.
The advantages of this valve over current mechanical valves is that, due to the effective and laminar flow characteristics, as well as the simple locking mechanisms, there is a reduced chance of valve thrombosis, and the need for anti-clotting drugs is therefore limited.

It was also confirmed that the new valve more than meets the published FDA (Federal Drug Agency) requirements, which determine the minimum standards of valves for human use in the US.

The redesigned valve also has a very low platelet activation impact, which is responsible for platelet thrombosis and leads to valve thrombosis or strokes. This valve is another heart-valve project by the centre, which is also in the process of evaluating a tri-leaflet polyurethane valve developed by them.


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