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11 August 2021 | Story Dr Cindé Greyling | Photo Supplied
Art lover Prof Janine Allen-Spies

Prof Janine Allen-Spies is an artist, lecturer in Fine Arts, and image philosopher from the UFS Department of Fine Arts. She teaches painting, drawing, and conceptual art to pre-graduate students and supervises postgraduate students in Fine Arts and other creative practices. In 2020, she was awarded the Stals Prize for her valuable role as a visual artist, academic, mentor, lecturer, activist, and supporter of art. 

What is the best thing about your job?
Working with artists and students who are energetic and passionate and love talking about art. 

What is the best and worst decision you have ever made?
As a second-year Art student, I modelled a psychedelic-looking bikini at a vintage clothing fashion show. Still makes me cringe! The best decisions weren’t really mine – they were godly interventions, so I can't claim them.

What was/is the biggest challenge of your career?
The biggest challenge is to make art. Even in the best circumstances, artmaking is ecstasy and agony. My biggest challenge as a mom is that I have two teenagers at home – working with students doesn't mean you know anything about younger teenagers.

What does the word woman mean to you?
As one of six sisters, I learnt that ‘woman’ implies diversity. We are all entirely different. Luckily, I don't have any preconceived ideas; all people should strive to be full-bodied human beings.

Which woman inspires you, and why?
Hypatia of Alexandria, Emily Hobhouse, Frida Kahlo, Princess Diana, and Caster Semenya – all women who do not fit into any mould. I am also inspired by my friends and my sisters and a lot of other local women.

What advice would you give to the 15-year-old you?
Make more of an effort to not grow up! Enjoy the beach, because one day you will not live close by. Your body is your own to take responsibility for and to love. Be strict with boyfriends and learn how and when to end a relationship, because nobody teaches you that.

What is the one self-care thing that you do? 
At the moment, the selfcare thing is visiting Nick, the hairdresser of Bella Donna who can fix, colour, and cut my hair, because managing my hair myself is just impossible.

What makes you a woman of quality, impact, and care?
I try to be self-reflective. To forgive and to be accepting are very important; we all have our fault lines, and we should work with each other's shortcomings. 
 
I cannot live without … coffee and ‘my’ psychologist.
My secret weapon is … honesty, and if my honesty fails, it will be having a Plan B.
I always have … fashion clothing items, even if I must make or alter clothing myself. My grandmother was a seamstress and we learnt to love clothing design.
I will never … again take the Free State landscape for granted.
I hope … poverty in the country will be addressed aggressively and in a more directed manner – which 
includes active participation and engagement of all people in South Africa.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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