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12 February 2021 | Story Leonie Bolleurs | Photo Charl Devenish
Dr Alice Ncube says that since coming to South Africa and working with vulnerable communities in the disaster (risk) management field, she has gained extensive knowledge and perspectives on the real-life situations of humanity.

While working in human resources and industrial-relations management portfolios, Dr Alice Ncube saw a window of opportunity to get into research, focusing on the challenges that was threatening the human capital management sectors and the general operations of governments and the private sector. 

Today, Dr Ncube is teaching students and doing research in the Disaster Management Training and Education Centre (DiMTEC) at the University of the Free State (UFS), where she is a Senior Lecturer and Programme Director.

On 11 February – International Day of Women and Girls in Science – the UFS is celebrating Dr Ncube, who chose to be a scientist due to her desire to make a difference. 

Being a migrant facing several challenges in her host country motivated her to do her PhD on international migration, specifically on women from developing countries to other developing countries such as South Africa.

Her research also covers related topics, including social vulnerability and resilience, international forced migration, gender issues, climate change and adaptation, and sustainable livelihoods of disadvantaged communities.

Demystifying perceptions

“Many persons who do not reside in the country believe that South Africa is a land of opportunities – socially, politically, and economically – due to its position on the African continent. This all-round positive picture of the country painted to the outside world is the main reason for the huge inflow of migrants into the country,” believes Dr Ncube. 

She envisaged that her study would assist in demystifying the perception that migrants are those who come to a host country to take local jobs and put pressure on local resources.

“I felt that gender migration in this space is under-researched, particularly migration of women. Migration is not gender neutral, but gender biased, as evidenced by the 1960s and early 1970s, where terms such as ‘migrants and their families’ were coded to refer to male migrants and their wives and children. Although women were nearly invisible, there is evidence of them migrating as independent agencies and also taking along their families, including husbands,” she explains.

Exploring the coping and adaptation strategies that women employ in the host country, she found that although faced with many challenges, the migrant women cope and adapt well.

Her research as well as her work of more than 10 years with the vulnerable communities, including migrants, has established that the resilience of vulnerable communities is bigger than the intervention strategies that governments and other stakeholders envisage.

People are hungry for knowledge that will better their lives. – Dr Alice Ncube

Impacting lives

“Since coming to South Africa and working with vulnerable communities in the disaster (risk) management field, I have gained extensive knowledge and perspectives on the real-life situations of humanity, let alone in our continent and region,” she says.

She has worked with government departments at local, district, provincial, and national levels in an effort to change the conditions faced by poor, marginalised, and disadvantaged communities. Dr Ncube was also involved in community capacity-building activities through short courses and short learning programmes. 

She considers the training she has presented as one of the biggest achievements of her life. “People are hungry for knowledge that will better their lives.” 

“This has been so fulfilling to me as I have made an impact on the lives of the people,” says Dr Ncube.

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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