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26 July 2021 | Story Nonsindiso Qwabe | Photo Nonsindiso Qwabe
On top of the Drakensberg. The ARU and Witsieshoek Mountain Lodge research team are, from the left: Grant Martin, Dr Ralph Clark, Jan van Niekerk, Prof Aliza le Roux, Prof Peter Taylor, and Dr Sandy Steenhuisen.

All mountains around the world have native and non-native species that are expanding their ranges quite dramatically; however, little research has been conducted towards understanding the long-term redistribution of species and the effects of global change on biodiversity.


The Afromontane Research Unit (ARU) on the University of the Free State Qwaqwa Campus – as part of the Mountain Invasion Research Network – has secured a two-year EU Horizon 2020 project under the Department of Science and Innovation, which will be looking at the mechanisms underlying the success and impact of range-expanding species on biodiversity and ecosystem functioning.

On Monday 19 July 2021, the ARU took a few of its researchers on a scenic helicopter ride to the summit of the Drakensberg for an alpine field-experiment site inspection of the Mont-aux-Sources peak, one of the highest sections of the Drakensberg range. This site has been identified for the project which the research unit will be leading on mountain research.

ARU Director, Dr Ralph Clark, said the project would explore the effects of global change, biological invasions (when species invade new geographic regions), as well as climate and land-use change. He said experiments were needed to explore the various possibilities and to test the extent to which species respond to experimental treatments. The project would therefore be conducting experiments for two years using open-top chambers – causing an increase in temperature of 3 or 4 degrees to what you find naturally – on plant species from lower down to the top of the mountain, to see how they function. “This will give us an idea of whether they will be able to survive in global warming scenarios. If temperatures get warmer, we might start seeing a lot of plants up here that we wouldn’t otherwise find here.”

Dr Clark said little is known about the long-term monitoring of species distribution and the effects of global change. Implementing the project in the Maloti-Drakensberg alpine area will therefore put the area in the global mountain research arena. The elevational gradient in the Maloti-Drakensberg Mountains provides space to explore the key processes underlying the variation in species elevation with climate change. “One of the things we don’t know much about are alpine systems. We are hoping to establish a long-term alpine research site and try to add as many studies as we can. The more science we can bring up here, the more we can know about mountain life. What happens on mountains has a lot of impact on social dynamics.

“This project is looking to see what is driving range expansion. Every mountain has its own context. In the Swiss alpine, fires are not a big factor, but fires are one of the biggest factors on our mountains. Some of our native and non-native species are therefore fire-driven, so as fire increases, you might have them spreading faster.”

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School of Medicine – heartbeat of the UFS
2015-06-24

Photo: Charl Devenish

During the past year, the School of Medicine at the University of the Free State celebrated several successes in the field of research and cooperation agreements. These successes allow the school to continue delivering world-class teaching to some of the country’s top students.

Earlier this year, a research team from the Department of Medical Microbiology under the guidance of Prof Felicity Burt, received a grant of R500 000 to conduct research on Congo fever (CCHF). Prof Burt is an internationally-recognised expert on Congo fever. The funding that has been awarded will be used to profile immune responses against CCHF viral proteins, and investigate mechanisms and strategies to enhance these immune responses. This study may contribute to the development of a vaccine against this deadly virus.

Prof Stephen Brown from the Department of Paediatrics and Child Health’s expertise and commitment to paediatric cardiology gained him the title of Bloemfonteiner of the Year. Under the leadership of Prof Brown, the department has performed many breakthrough operations and procedures. The most recent of these, was the first hybrid procedure in the country which was performed in November 2014. The department also has an ultramodern hybrid heart catheterisation suite.
 
Prof William Rae from the Department of Medical Physics focuses on medically-applied radiation. Together with his department, they are looking at quantitative radiation dosages. The research is particularly crucial for the successful treatment of cancers. Through this research, it is possible to ensure that patients receive the appropriate radiation dosages in order to obtain the desired effect without the patient being affected negatively.

Dr Nathanial Mofolo, Head of the Department of Family Medicine in the School of Medicine, is since 2006 involved at various levels of hospital management regarding quality assurance, patient safety, clinical and infection management, as well as administration. He is currently curator of internal medical students for four of the UFS’s teaching hospitals. His department is currently focusing on the National Health Plan, HIV and tuberculosis, teaching and learning, as well as service delivery in family medicine.
 
Prof Francis Smit manages the team that, to their knowledge, decellularised the first primate heart. The method has been applied successfully on rat and pig hearts by researchers in America. Recently the team also successfully cultivated beating heart cells ? those of a rat ? in their laboratories. The research is in line with what researchers in Europe and America are working on. In the long run, the research project aims to attempt ‘building’ a heart that could be used for the purposes of organ donation.

The UFS is also home to the only metabolic research unit in the country. The unit was established to focus research on obesity, type II diabetes, metabolic bone diseases and all related diseases. This includes diseases such as diabetes, cholesterol, cancer, psoriasis, lymphoedema, fatigue, high blood pressure, gout, arthritis, fibrosis, skin disorders, PMT, migraine, insomnia, gall and kidney stones and related infections, and obstructive sleep apnea. The unit is a joint initiative between the UFS and Christo Strydom Nutrition. Mr Christo Strydom, a nutritionist and world renowned in the treatment of lymphoedema, invested R5 million in the establishment of this unit at the UFS.  Christo Strydom is also the founder and owner of Christo Strydom Nutrition.

The School of Medicine at the University of the Free State is the only unit on the continent offering in-depth modules in clinical simulation. The Clinical Simulation Unit on the Bloemfontein Campus of the UFS, headed by Dr Mathys Labuschagne, is regarded as the flagship unit of the school and boasts high-technology equipment where students can practice their clinical skills before applying those skills in the real world.
 

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