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23 November 2021 | Story Leonie Bolleurs | Photo Supplied
With her talk on ‘Breaking the walls of darkness’, Emmie Chiyindiko came in second out of the 74 pitches presented at the recent Falling Walls Science Summit.

“I need you to take a moment and imagine trying to do everything that you do every day … without reliable energy. Or I’ll ask you this … How far would you walk to charge your phone if you didn’t have electricity? Would you walk for hours? Kilometres?”

“Well, that’s what millions of people in sub-Saharan Africa do daily to charge their phones. One billion people globally don’t have access to electricity in their homes and in sub-Saharan Africa, more than half of the population remains in the dark.”

This was the introduction to Emmie Chiyindiko’s talk at the recent Falling Walls Science Summit earlier this month. Emmie, who is a PhD student in Chemistry at the University of the Free State (UFS), came in second out of the 74 pitches presented with her talk on ‘Breaking the walls of darkness’ in the ‘Breakthrough of the year in the emerging talents category’.

Falling Walls Lab is a world-class pitching competition, networking forum, and steppingstone that brings together a diverse and interdisciplinary pool of students, researchers, and early-career professionals by providing a stage for breakthrough ideas, both globally and locally. 

Emmie, who sees getting out of bed every morning as just another opportunity to “be the exceptional young black female scientist that I am”, won the local Falling Walls Lab in Cape Town in October, which resulted in her going through to the finals in Berlin. She plans to host the Falling Walls Lab in Zimbabwe, her homeland, next year. 

This innovator and science communicator, whose work has been covered in Forbes Science, News24, and the Sunday Times, among others, refers to her obtaining second place on the international stage for her research as “a tremendous achievement and a new height in my science communication career. That level of recognition from the world leaders in science, technology, and science engagement cannot be overstated”.

Ending energy poverty

She believes Sustainable Development Goal 7 – leaving no one behind and eradicating global poverty – must be preceded by intentional efforts to end energy poverty. “My research on dye-sensitised solar cells (DSSC) with special metal complexes is among the most interesting alternatives to conventional solar cells.”

Emmie explains: “The design of the cells is inspired by photosynthesis – that good old process plants use to transform sunlight into energy via chlorophyll. Instead of a leaf, the cells start with a porous, transparent film of eco-friendly titanium dioxide nanoparticles. The film is also coated with a range of different dyes that absorb scattered sunlight and fluorescent light. When sunlight hits, it excites the electrons in the dye, creating an endless supply of energy. 

The bright side of this research is that there are several benefits to this invention. It produces energy that is cheap, reliable, and relatively simple and inexpensive to produce. Emmie adds: “These next-generation cells also work impeccably in low-light and non-direct sunlight conditions, providing all-year-round energy with no disruptions. DSSC is also three times cheaper than conventional cells and produces 40% more energy.”

Improving livelihoods 

She continues: “It does not degrade in sunlight over time as do other thin-film cells, making the cells last longer, and requiring less frequent replacement. DSSCs are also mechanically strong, because they are made of lightweight materials and do not require special protection from rain or abrasive objects.”

Emmie has proven that solutions to our current energy situation are available. “We are on the cusp of an energy revolution, and we must act now. Solutions are available, and if we do not seize them during a time of crisis, when will we?”

She believes that creating technology like this can end the energy crisis and improve livelihoods. “Billions of people simply lack enough energy to build a better life. Affordable, abundant, and reliable energy can go a long way to store food, power life-saving medical equipment, and run trains and factories. It can help communities to grow and prosper and to access opportunity and dignity. Societies where people have access to energy have lower childhood mortality, a higher life expectancy, they eat better and drink cleaner water, and have a better literacy rate.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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