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19 October 2021 | Story André Damons | Photo Supplied
Prof Motlalepula Matsabisa, Director of Pharmacology, has received a DSI high-end infrastructure (HEI) grant to establish one of the most advanced modern Pharmacology GLP-accredited research and development laboratories in the country, and possibly in the region.

The Department of Pharmacology at the University of the Free State (UFS) will establish one of the most advanced modern Pharmacology GLP-accredited research and development laboratories in the country, and possibly in the region, after receiving a grant of R58 million. 

Prof Motlalepula Matsabisa, Director of Pharmacology, has received a DSI high-end infrastructure (HEI) grant to build the laboratory, which will be a centre of excellence for the government, the World Health Organisation (WHO), and the African Union’s (AU) Commission for Social Development. The grant will also be used to build an herbal medicines production/manufacturing facility, as well as piloting a health facility for traditional medicines. 

“I am excited to bring this huge grant to the UFS and look forward to the institution working effortlessly to become one of the leaders in this initiative. We aim to respond to our local, regional, and international research needs, our product development and commercialisation requirements, and to be competitive according to current international standards. The facility will be a unique place to learn and put theory into practice and develop the research from the bench to the hospital bedside,” says Prof Matsabisa. 

Laboratories will host students, researchers, and scientists

According to him, the research and development laboratories, as a centre of excellence, will host students, researchers, and scientists from the continent in order to practicalise and strengthen bilateral African science and technology development, as well as South-South collaborations, while maintaining its international outlook. This will lead to proper drug discovery, drug development, and product development, serving a number of clients, including communities, traditional health practitioners, the pharmaceutical industry, as well as policy makers. 

“We will develop the facilities to compete in international herbal-medicine markets.  With this injection of funding, as well as support from all our clients, namely universities – the UFS in particular – the government, and the WHO and AU, including support from traditional health practitioners, communities, and the herbal pharmaceutical industry, failure has no definition in our vocabulary and is a distant thought.”

“We will develop effective, safe, quality products under one roof – from basic and clinical research to finished, final, marketed proprietary products based on indigenous knowledge systems (IKS) and our iconic traditional medicinal botanicals,” states Prof Matsabisa.     

Under the leadership of Prof Matsabisa, the department has recently also been awarded an annual Technology and Innovation Agency Platform (TIA) grant of R17 million for the next five years. This research and teaching programme, known as African Medicines Innovations and Technologies Development (AMITD), will help to recruit and employ the best skills throughout the research, development, and herbal-medicine manufacturing value chains. 

“These investments will enable the university to play a large and key role in realising the dream of a sustainable propriety ATM industry to make an impact on health and job creation.”

AMITD will act as a national training and capacity development facility in drug research and development (R&D), and the formulation and production of quality, safe, effective, and well-researched medicines.  We hope to not only train students, but also technicians, researchers, and traditional health practitioners. The facility will afford postgraduate students a unique opportunity for research development and training at this innovative platform, with world-class specialised infrastructure and IKS academic leadership. Capacity development will be strengthened through postgraduate bursaries and postdoctoral funding by the UFS. The collaboration with the private sector will further afford opportunities for research capacity development through postgraduate job opportunities and internship training at collaborating industry partners.

Prof Matsabisa, who is also leading Africa’s fight against the COVID-19 pandemic after being appointed chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19 last year, further states that both the laboratories – the health and the production facilities – will be state-of-the-art, with the most modern research and production equipment.

Mr Werner Nel, Director: Research Development; Dr Nico Walters, Technology Development expert consultant, and
Dr Glen Taylor, Senior Director: Research Development, were part of the ‘A-Team’ that played a role in the Department
of Pharmacology receiving a R58 million grant. (PhotoSupplied)

Platform to strengthen collaborative efforts

The university, with its commitment, proven leadership in IKS for health, extensive IKS collaborative networks across the globe, available research and pharmaceutical product development expertise, state-of-the-art manufacturing equipment and supportive research capacity development programmes, is ready and eager to host such a production facility on its Bloemfontein Campus for later growth and expansion. The production and laboratories will be ideally situated in Central South Africa, so that the facility can be accessible to all.


“We see this facility as a platform to strengthen our collaborative efforts with industry, communities, and traditional health practitioners to address their research, R&D and production needs, and strive to contribute to the local development of an African medicines-based pharmaceutical industry. The facility will also be a national asset for the training of postgraduate students and scientists in this field, with more emphasis on assisting those institutions in rural provinces,” added Prof Matsabisa. 

All of this would not have been possible without the ‘A-Team’ of Dr Glen Taylor, Senior Director: Research Development, Dr Nico Walters (expert consultant for technology development), and Mr Werner Nel (Director: Research Development), says Prof Matsabisa. 

“There are a lot of people supporting IKS directly and indirectly – from Rectorate to the Faculty of Health Sciences and the Department of Pharmacology, as well as the cleaners who ensured a clean place when the funders came for their visits, support from Pharmacology staff, students, and postdoctoral fellows. I acknowledge the unwavering support of my HOD, not forgetting colleagues and managers of other departments who also contributed to the success of this grant directly or indirectly.”

“However, in every collaboration and teamwork there are those who take the idea as theirs and ensure that they live with this idea and grow with it; I call them the A-Team,” says Prof Matsabisa. 

According to Dr Taylor, the UFS research strategy recognised the important role of IKS and African traditional medicines in the health and socio-economic fabric of our society. “Over the past five years, we have systematically built and invested in an IKS platform to become a centre of excellence, not just institutionally, but also with a national, regional, and international standing,” says Dr Taylor.

Big grant is a first 

Dr Walters says a number of government initiatives aimed at community development, job creation, scientific value addition to local products, and the utilisation of our natural resources – land and marine – have been developed. These initiatives include the IKS Act 6 of 2019, AsgiSA, Batho Pele, and the Biodiversity Initiative, aimed at the sustainable development and commercialisation of South Africa’s natural resources. 

“But never before has such a bold funding decision been made in the IKS funding sphere in the country like this one. I have been in this space of technology development and IKS development for years. This is not only the first such big grant for the UFS, but also for the country and region in terms of IKS.” 

“It was a compelling value-for-money proposal, and very difficult to shoot down with so many letters of support emanating from other universities, research councils, government departments – provincial and national – our own SAHPRA, and many other letters from the WHO, WIPO, UN bodies, including from other international universities. This is not surprising, given the recognised international scientific standing of Prof Matsabisa on all the continents. But again, more importantly, not to forget the letters of support for this facility from the pharmaceutical industry and organisations of traditional health practitioners,” says Dr Walters.   

“We would also like to acknowledge the support – through his letter of support – from our Rector and Vice-Chancellor, Prof Francis Petersen, and the institution for the idea and proposal content,” says Prof Matsabisa. 

News Archive

Association of Former SRC Presidents – first of its kind
2013-08-19

 

Some of the former SRC presidents who attended the inaugural dinner were, from the left: Roelf Meyer, Bloemfontein Campus 1970; Dr More Chakane, Qwaqwa Campus 1990; vice-chairperson of the AFSP; Dr Anchen Laubscher, first woman president of the Bloemfontein Campus 2003; and Prof Voet du Plessis, Bloemfontein Campus 1967/8.
Photo: Stephen Collett
19 August 2013

The University of the Free State (UFS) made history this weekend with the establishment of its Association of Former SRC Presidents (AFSP) – the first association of its kind after the merging and incorporation of public institutions in 2003–2004.

Twenty-two former SRC presidents attended the inaugural dinner to launch the association on Women's Day, Friday 9 August 2013, and recognised especially the attendance of all four female presidents that previously chaired the SRC. Other guests included former rectors and chairpersons of the UFS Council, as well as chairpersons of the Alumni.

The attending presidents served during the period 1967–2012, either at the former University of the Orange Free State (UOFS), the Qwaqwa Campus of the former University of the North, South Campus of the former Vista University and the University of the Free State.

“Your very personal narratives as former student leaders during the troubled past of our history in South Africa matter most as you design the questions for and purpose of an authentic conversation with student leaders today – this will set your association apart from others," said Rudi Buys, Dean of Student Affairs.

Former SRC president of 1975/6 and now founding member and chairperson of the association, Dr Michiel Strauss, said that this is the opportunity for former student leaders to give back to the younger generation.

“It is true that many middle-aged white South Africans have a deep sense of debt and obligation towards the youth of our country. We owe them an apology for the discrepancies of the past. This apology should be more than just words. Deeds of reconciliation and restitution must be seen.

“As for myself; I was president of the SRC of the then UOFS in the same period in which the biggest part of the youth of South Africa suffered so much in their struggle for freedom in our country.

“In my personal capacity, as well as in my official capacity as SRC president, I did nothing to try and understand and/or co-operate in the struggle of my peers. This fact haunts me until this day.

“The question then for people like me and so many others, is: Where do I invest my time and energy and passion for this country? Where will my contribution make a real difference? There is no better answer to this burning question than to invest in the human resources in our beloved South Africa, and more focused – to invest in the young people.

“There is something meaningful and beautiful happening at the UFS and it is now a leader in academic standards, reconciliation, leadership formation and nation building. I can think of no better place to make my small contribution,” Dr Strauss said.

“As former student leaders, we have a sense of purpose to contribute to the university and there is no better time to start than now. It is my privilege to be part of this great initiative and I look forward to what will be achieved,” said Dr More Chakane, deputy chairperson of AFSP and former SRC president of the Uniqwa Campus of the University of the North in 1990 (now the Qwaqwa Campus of the UFS).

Roelf Meyer, known for the prominent role he played in the negotiations to end apartheid in South Africa and chairperson of the Civil Society Initiative (CSI) of South Africa, said his time as a leader at the university has given him the opportunity to apply and use his skills and experience and share it with the new leaders of the institution. "The UFS is highly regarded because of the exceptional standards and excellence portrayed by its senior leadership. Where I can make a difference, I'll do it with pleasure and pride," he said. Meyer served as SRC president in 1970.

The association met on Saturday 10 August 2013 to adopt its interim constitution and consider operational matters, while also reaching agreement on its core functions in support of its purpose to transfer change leadership skills to incumbent student leaders and mediate meaningful contributions of Alumni to the growth of the university.

“We greatly value the declared intention of AFSP to work with the university to design meaningful and sustainable mentorship programmes to support and guide student leaders on campus, and have pledged our support in this regard,” said Buys.

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