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21 September 2021 | Story Leonie Bolleurs | Photo 3T Photography
The new US Consul General, Vincent Spera, recently visited the UFS Bloemfontein Campus. He was hosted by the Office for International Affairs. Pictured here are Cornelius Hagenmeier, Dr Dionne van Reenen, and Vincent Spera.

Vincent Spera, the new US Consul General, paid a courtesy visit to the University of the Free State (UFS) on 16 September 2021, where he was hosted by the Office for International Affairs on the Bloemfontein Campus.

The aim of his visit was to strengthen relationships with the UFS. The university has a rich academic collaboration with US higher education institutions, as evidenced by the 313 co-authored papers published by UFS authors with collaborators at 291 institutions in the United States (US) between 2018 and 2020.

In the past eight years, close to 150 international students from the US – from postdoctoral fellows up to undergraduate level – studied at the UFS. The UFS is also home to more than 30 research fellows from the US. 

Cornelius Hagenmeier, Director of the UFS Office for International Affairs, says he would like every student to have an international experience. “I believe it is doable. Through virtual exchanges, curriculum internationalisation, and internationalisation at home, we can make this happen,” he says. 

Prof Corli Witthuhn, Vice-Rector: Research, emphasised the importance of US collaborations for the university. She appreciates the support afforded by the US Consulate for the manifold collaborative activities connecting the UFS with the US. 

A number of UFS researchers who is collaborating with the US on certain projects interacted with Spera during his visit. 

USDP Programme

According to Prof Corlia Janse van Vuuren, Head: UFS School of Health and Rehabilitation Sciences, the Faculty of Health Sciences’ biggest academic collaboration with US higher education institutions is through the University Staff Development Programme (USDP).

She says: “The USDP is an enriching journey for the group of UFS academic staff members who participate as PhD candidates in this initiative. The international connection with the University of Virginia (UVA), where mentors are assigned to most of the PhD candidates, is raising the quality of the qualification.”

This doctoral training programme supports the doctoral degree studies of a cohort of six academics from the UFS and five from the University of Venda (Univen) in the field of global health. The group of PhD candidates are from different disciplines in health sciences, including Anaesthesiology, Orthopaedics, Obstetrics and Gynaecology, as well as Occupational Therapy in the Allied Health Sciences. One of the candidates completed his studies and is working with UVA on a number of publications; the rest of the candidates will complete their studies in 2022 and 2023. 

“These doctoral candidates are also very much involved in student training as well as medical specialist training. This increases the quality of our medical specialist training in the faculty. Undergraduate student training also indirectly benefits from this initiative,” she adds.

Dr Gray Magaiza, Acting Assistant Vice-Dean and Programme Director in the Department of Sociology on the UFS Qwaqwa Campus, is in agreement about the value of the USDP programme. He himself received his PhD qualification through the programme. 

US Consul General, Vincent Spera, and Prof Corli Witthuhn, , Vice-Rector: Research, Innovation and
Internationalisation. (Photo: 3T Photography)

“The programme opened many doors for me. It was one of the best experiences I ever had, especially the support I received in completing my studies. The quality sought by US supervisors are also quite high,” he says. 

Spera says it is wonderful to hear about the collaborations taking place. “It is through these partnerships that connections between South Africans and Americans are allowed to grow exponentially.”

“PhD development is critical, and we want to increase the number of PhD graduates, particularly staff members with PhD qualifications. We appreciate the collaboration with the US in research and capacity development, which together with internalisation are high priorities,” Hagenmeier says.

Fulbright Scholarships

Prof Lynette Jacobs, Head of Research on the UFS South Campus, acknowledged the contribution that the Fulbright programme has made to the UFS South Campus. Four years ago, the visit of one Fulbright scholar, Prof Barbara Howard from the Appalachian State University, evolved to a long-term commitment from individuals and the institution to continue working on intercultural and international projects, as well as research collaborations. 

Together with academics from Novgorod State University in Russia, Prof Jacobs and Prof Howard are collaborating on the development of virtual capacity building programmes, specifically to support internationalisation. The courses include international cross-cultural communication skills, leadership in virtual international teams, sustainable development, and using technology meaningfully in a virtual international space. 

“This is a wonderful testament to not letting ourselves get fixed to one kind of thinking. It does not always have to be the five-year PhD or two-year academic Fulbright programme, but there are all sorts of models that can make a difference,” responds Spera.

Guided by Dr Dionne van Reenen, Senior Researcher in the Unit for Institutional Change and Social Justice, Spera undertook a walking tour of the UFS Centenary Complex and the Unit for Institutional Change and Social Justice. He appreciated the information shared about the UFS transformation process, and the collaboration between the US and the unit. 

According to Mbali Moiketsi, Study Abroad coordinator, the US consulate has supported and offered guidance to UFS students and staff to pursue study abroad opportunities with the assistance of International Affairs. 

Recently, the university had two recipients of the Fulbright foreign student scholarship and has to date hosted three Fulbright visiting scholars. These recipients have contributed to the growth of the partnership and has increased relations with universities in the US. The partnership is set to continue, offering broad opportunities for the UFS staff and students. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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