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05 August 2022 | Story Leonie Bolleurs | Photo Supplied
Marike Stander
For the first time in her life, Marike Stander accompanied a group of researchers for their annual relief expedition with the SA Agulhas II from Cape Town to Marion Island, where she assisted with fieldwork and data collection. Here she is pictured at the snow-covered Karookop.


The Prince Edward Islands are the most southerly part of South Africa’s official territory and consist of Marion Island and Prince Edward Island. On Marion Island, about 270 km² in size and situated in the sub-Antarctic Indian Ocean, 1 920 km from the South African shore, activities are restricted to research and conservation management. 

This is where Marike Stander, Lecturer in the Department of Geography at the University of the Free State (UFS), was granted the opportunity to assist a research group led by Prof Werner Nel (University of Fort Hare) and Prof David Hedding (Unisa) – based on her knowledge and experience in tracer sampling. 

Back home, Stander is working to complete her doctoral research, investigating the often-overlooked major issue of soil erosion. She believes the management of soil erosion, a global issue, is key. According to her, it impacts the storage of carbon and nutrients, and therefore the production of food, but it can also act as a pollutant in water sources.

Fieldwork and data collection

She was approached by the Sub-Antarctic Landscape-Climate Interactions (SANAP-LCI) Research Group, a project funded by the South African National Antarctic Programme-NRF. One of their research objectives is to explore the viability of using geochemical tracers in the substrate on Marion Island, the focus of Stander’s doctoral research. 

With the support of the UFS Faculty of Natural and Agricultural Sciences and the Department of Geography, she was released to accompany the research group for the first time in her life on their annual relief expedition with the SA Agulhas II from Cape Town to Marion Island, where she assisted with fieldwork and data collection. During this three-week field campaign, Stander collected sediment samples for the tracer project, as well as rock and peat samples.

With the SANAP-LCI group collaborating with research labs in the United Kingdom and France, she was able to bring her expertise to the table, while at the same time learning about other geochronological techniques and field methods.  

She was also excited about the exposure to the work of a myriad of researchers in various fields from around the world. Stander says in a time when the importance of interdisciplinary and multidisciplinary work is being emphasised, it was invaluable to meet and learn from various distinguished scientists.  “It changes your perspective and allows your mind to not only think outside the box, but also to think about all the interconnected boxes and how they affect each other.”

She believes being exposed to various sampling strategies from different scientists also broaden one’s skill set and experience. “Using your capabilities and skills in a different setting builds depth to your skill set and expands your horizon.”

Volcanoes and albatrosses 

Very few people get the opportunity to visit Marion Island. Thus, just the chance to visit and experience life on the island is described by many as one of their most memorable events. Always fascinated by volcanic features, Stander was completely captivated by this relatively young volcanic island. “There are so many interesting features, such as the pahoehoe and a’a lava flows, as well as the numerous scoria cones,” describes Stander, who cannot believe that she managed to cover the vast distances in gumboots, the only footwear that are effective to cross anything – from razor-sharp rocks to deep waterlogged mires.

She was also overwhelmed by the flora and fauna on the island.  “It is so very different from what we are used to and from what I’ve experienced before.  Seeing these animals in a relatively untouched remote location really captivated me,” she says. 

“More specifically, I fell in love with the albatrosses.  These remarkable seabirds cover vast distances over the ocean looking for food. They are unfortunately threatened by the invasive mice on Marion Island.” Stander invites people to help organisations such as Mouse-Free Marion to take on the difficult task of eradicating these mice. Find them at www.mousefreemarion.org.

On a lighter note, Stander also learnt a thing or two that was totally new to her. For instance, that there are radio telescopes installed on the radio-quiet Marion Island, searching for the universe’s first stars. And that male elephant seals that drive out all other male competitors during mating season are called ‘beachmasters’. She learned that these ‘beachmaster’ bulls have a harem of female elephant seals and can weight up to three tons.


• She wishes to thank Prof Werner Nel, Prof David Hedding, and Dr Liezel Rudolph (UFS) from the SANAP-LCI project for affording her the opportunity to join the expedition. She also thanks the SANAP-NRF and the Department of Forestry, Fisheries, and the Environment for making the expedition possible. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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