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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

Plant scientists address wheat rust diseases at SASPP congress
2015-02-02

Pictured from the left are: Prof Zakkie Pretorius, Dr Botma Visser and Howard Castelyn.
Photo: Supplied

In his research, Dr Botma Visser, researcher in the Department of Plant Sciences at the University of the Free State, highlighted the population dynamics of the stem rust fungus (Puccinia graminis f. sp. tritici) in Southern Africa. In recent years, two foreign stem rust races were introduced to South Africa, and a local virulence adaptation occurred in a third.

All of these races form part of the Ug99 group, a highly virulent collection of rust races endangering wheat production in many parts of the world. Despite the fact that half of the members of the Ug99 race group is prevalent in South Africa, Dr Visser’s work has clearly shown that Ug99 did not have its origin here. This emphasised the need to include neighbouring countries in the annual stem rust surveys, to proactively identify new races that could threaten local wheat production. In his research, Dr Visser also mentioned the way in which he has optimised modern molecular tools to accurately detect Ug99 isolates.

Dr Visser is one of three scientists from the Department of Plant Sciences that addressed delegates attending the biennial congress of the Southern African Society for Plant Pathology (SASPP) on the Bloemfontein Campus earlier this month on progress regarding research on wheat rust diseases conducted at the UFS.

Howard Castelyn, a PhD student in Plant Sciences, presented his research on quantifying fungal growth of the stem rust pathogen in wheat varieties displaying genetic resistance. This resistance, which is best expressed in adult plants, has the potential to remain durable in the presence of new rust variants. His presentation at the congress focused on optimising microscopic and molecular techniques to track fungal development in stem tissues of adult plants. These results now allow scientists to link rust infection levels and cellular responses with particular resistance genes expressed by the wheat plant, and contributing to the understanding and exploitation of durable resistance.

Prof Zakkie Pretorius presented his research, explaining how new genetic diversity for resistance to the stripe (yellow) rust fungus (Puccinia striiformis) is discovered, analysed and applied in South Africa. This research, conducted in collaboration with Dr Renée Prins and her team at CenGen, is unravelling the genetic basis of stripe rust resistance in a promising wheat line identified by Dr Willem Boshoff, a plant breeder at Pannar. The line and DNA markers to track the resistance genes will soon be introduced to South African wheat breeding programmes.

The rust research programme at the UFS contributes significantly to the successful control of these important crop diseases.

In addition to the contributions by the UFS, rust fungi featured prominently at the SASPP, with first reports of new diseases on sugar cane and Acacia and Eucalyptus trees in South Africa. A case study of the use of a rust fungus as a biological control agent for invasive plant species in the Western Cape, was also presented.

 

For more information or enquiries contact news@ufs.ac.za .

 

 

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