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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

UFS Cardiovascular Research Centre a South African solution to continental crisis
2015-11-30

From left are: Dr Robert Kleinloog, president of the Society of Cardiothoracic Surgeons of South Africa, Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), Prof Robert Frater after which the Robert W M Frater Cardiovascular Research Centre was named and Prof Francis Smit, head of Cardiothoracic Surgery at the UFS, at the launch of the new centre.
Photo: Johan Roux

“You don’t have to be in New York or any big city in the world to establish a cardiovascular centre that delivers work of world standards. I’ve learned that extraordinary things are achieved by ordinary people who apply themselves accordingly. This research centre is a South African solution to a continental challenge”.

These were the words of Prof Robert Frater at the opening of the new Robert W M Frater Cardiovascular Research Centre in the Department of Cardiothoracic Surgery at the University of the Free State (UFS) School of Medicine.

The centre, one of only two of the kind in the country, will focus on bioengineering and cardiovascular research. It was opened on Wednesday 18 November 2015 in the Francois Retief Building on the Bloemfontein campus.

The centre is named after Prof Robert W.M Frater in recognition of his vast contribution to the UFS. He is internationally recognised for his outstanding academic, clinical, and scientific contributions to cardiac surgery. Prof Frater has also been actively involved in research activities of the Department of Cardiothoracic Surgery for the last 10 years. In 2011, he received an honorary doctorate from the UFS.

Under the leadership of Prof Francis Smit, head of Cardiothoracic Surgery, the department has been described as a dynamic unit at the forefront of meeting the different changes in Southern Africa while maintaining an excellent clinical and academic track record.

At the opening, Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, thanked Prof Frater for his presence at, involvement in, and support of the UFS. “I am looking forward to working in collaboration with the department to make this university a research centre of excellence in the continent”, he said.

The centre has existing endeavours already in operation, including Population projects, Clinical studies, and Clinical pathology, to name three. In collaboration with the Central University of Technology, the University of Stellenbosch, and Charite University of Berlin, among numerous others, the centre will be an appropriate help to an African challenge.

Its introduction promises advanced research outcomes with the potential to make the Department of Cardiothoracic Surgery a world-class competitor.

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