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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

Harvard couple to present lectures on Biostatistics and Mathematics at the UFS
2015-12-07


Professor Donald Rubin

Prof Donald Rubin (John L. Loeb Professor of Statistics at Harvard University) and Elizabeth Zell (MStat - mathematical statistician in the Division of Bacterial Diseases) will visit the University of the Free State (UFS) where they will present lectures on their respective work.

Over his prestigious academic career, Prof Don Rubin’s 400 publications and 13 books have earned him around 180 000 citations at an h-index of 113. He is one of the most cited statisticians/mathematicians/economists/psychologists in the world over the last 10 -15 years. He has supervised 35 PhD candidates as sole-supervisor, 17 more as co-supervisor, with a further eight in the pipeline.

Prof Rubin who will meet with UFS academics in the Department of Mathematics and Actuarial Sciences will also deliver a lecture: Rerandomisation to improve covariate balance in experiments.

Randomised experiments are the “gold standard” for estimating causal effects, yet in practice, chance imbalances often exist in covariate distributions between treatment groups. If covariate data are available before units are exposed to treatments, these chance imbalances can be mitigated by first checking covariate balance before the physical experiment takes place. Provided a precise definition of imbalance has been specified in advance, unbalanced randomisations can be discarded, followed by a rerandomisation. This process can continue until a randomisation yielding balance according to the definition is achieved. By improving covariate balance, rerandomisation provides more precise and trustworthy estimates of treatment effects.

Prof Rubin received an honorary professorship from the Faculty of Natural and Agricultural Sciences at the UFS.


Elizabeth Zell

The lecture will take place on:
Date: Tuesday 8 December 2015
Time: 16:00
Venue: Albert Wessels Auditorium, Bloemfontein Campus

Zell earned her Master’s degree in Statistics at North Carolina State University, and for more than two decades, was an active bio-statistical researcher in various offices of the Centers for Disease Control (CDC). Since 2013, she has been the Principal Statistician and President of Stat-Epi Associates, Inc. Her 150+ publications have earned her 14 500 citations at an h-index of over 50. She is a Fellow of the American Statistical Association, and, in 2010, she received the Statistics Section Government Award for outstanding contributions to statistics and public health by the American Public Health Association. During her career at the CDC, she earned more than 20 CDC research awards and honours.

She will deliver two lectures at the UFS. The first is entitled A Potential Outcomes Approach to Documenting the Public Health Impact of the Introduction of PCV13 for the Prevention of Invasive Pneumococcal Disease. The topic of her second lecture is: Assessing the Effectiveness of Intrapartum Antibiotic Prophylaxis for Prevention of Early-Onset Group B Streptococcus Disease through Propensity Score Design

Elizabeth’s lectures will take place on:
Date: Wednesday 9 December 2015
Time: 10:45 and 13:00
Venue: West Block 111, Bloemfontein Campus

For more information, please contact Dr Michael von Maltitz at VMaltitzMJ@ufs.ac.za.

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