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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

New Division of Virology to deliver crucial services for HIV diagnosis and resistance testing
2015-12-14

The establishment of a Division of Virology within the Department of Medical Microbiology, under the joint auspices of the UFS and the National Health Laboratory Service (NHLS), reflects the continued growth within Virology.  Dr Dominique Goedhals, Head of the Division, says the division will also provide training of undergraduate medical students, medical technologists and technicians, and registrars.

The newly established Division of Virology at the University of the Free State will be one of only five laboratories in the country to be involved in crucial diagnostic and testing services for HIV viral load monitoring, early infant diagnosis, and HIV resistance testing.

The Virology Diagnostic Laboratory serves as the reference laboratory for all HIV National Priority Programme samples for the Free State and Northern Cape provinces.

Medical staff at the laboratory will provide a 24-hour consultative service, as well as outreach programmes to district laboratories in the Free State and Northern Cape where pathologists are not available. 

Dr Dominique Goedhals, Head of the Division of Virology, says this division, under the joint auspices of the UFS and the National Health Laboratory Service (NHLS), reflects the continued growth within Virology.

The division will not only deliver this critical diagnostic service, but will also focus on training and teaching, as well as research.

Teaching and training activities include teaching of undergraduate medical students, medical technologists and technicians, and registrars.  The postgraduate science programme has a high output of honours, master’s and doctoral students in Virology.  The intern medical scientist programme is also active, with five interns having successfully submitted their portfolios since the programme was implemented in 2010.

Research activities under the Head of Research, Prof Felicity Burt, have also expanded and continue to show increases in publication output and acquisition of grant funding.  Established research groups within the Division of Virology focus on vector-borne and zoonotic viruses, human papilloma viruses (HPV), and human immunodeficiency virus (HIV), as well as work with a number of international collaborators.


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