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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

Names are not enough: a molecular-based information system is the answer
2016-06-03

Description: Department of Plant Sciences staff Tags: Department of Plant Sciences staff

Prof Wijnand Swart (left) from the Department of
Plant Sciences at the UFS and Prof Pedro Crous
from the Centraalbureau voor Schimmelcultures (CBS),
in the Netherlands.
Photo: Leonie Bolleurs

South Africa is the second-largest exporter of citrus in the world, producing 60% of all citrus grown in the Southern Hemisphere. It exports more than 70 % of its citrus crop to the European Union and USA. Not being able to manage fungal pathogens effectively can have a serious impact on the global trade in not only citrus but also other food and fibre crops, such as bananas, coffee, and cacao.

The Department of Plant Sciences at the University of the Free State (UFS) hosted a public lecture by Prof Pedro W. Crous entitled “Fungal Pathogens Impact Trade in Food and Fibre: The Need to Move Beyond Linnaeus” on the Bloemfontein Campus.

Prof Crous is Director of the world’s largest fungal Biological Resource Centre, the Centraalbureau voor Schimmelcultures (CBS), in the Netherlands. He is also one of the top mycologists in the world.

Since the topic of his lecture was very pertinent to food security and food safety worldwide, it was co-hosted by the Collaborative Consortium for Broadening the Food Base, a multi-institutional research programme managed by Prof Wijnand Swart in the Department of Plant Sciences.

Reconsider the manner in which pathogens are identified

Prof Crous stressed that, because international trade in products from agricultural crops will expand, the introduction of fungal pathogens to new regions will increase. “There is therefore an urgent need to reconsider the manner in which these pathogens are identified and treated,” he said.

According to Prof Crous, the older Linnaean system for naming living organisms cannot deal with future trade-related challenges involving pests and pathogens. A system, able to identify fungi based on their DNA and genetic coding, will equip scientists with the knowledge to know what they are dealing with, and whether it is a friendly or harmful fungus.

Description: The fungus, Botrytis cinerea Tags: The fungus, Botrytis cinerea

The fungus, Botrytis cinerea, cause of grey mould
disease in many fruit crops.
Photo: Prof Wijnand Swart

Embrace the molecular-based information system

Prof Crous said that, as a consequence, scientists must embrace new technologies, such as the molecular-based information system for fungi, in order to provide the required knowledge.

He presented this very exciting system which will govern the manner in which fungal pathogens linked to world trade are described. This system ensures that people from different countries will know with which pathogen they are dealing. Further, it will assist with the management of pathogens, ensuring that harmful pathogens do not spread from one country to another.

More about Prof Pedro Crous


Prof Crous is an Affiliated Professor at six international universities, including the UFS, where he is associated with the Department of Plant Sciences. He has initiated several major activities to facilitate global research on fungal biodiversity, and has published more than 600 scientific papers, many in high impact journals, and authored or edited more than 20 books.

 

 

Biography Prof Pedro Crous
Philosophical Transactions of the Royal Society B


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