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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

UFS researcher explores the future cost of cancer
2017-01-10

 Description: 001 Dr Alicia Sherriff Tags: 001 Dr Alicia Sherriff

Dr Alicia Sherriff, Head the Department of Oncology
at the UFS Faculty of Health Sciences, co-authored
an article in the South African Medical Journal.

Photo: Charl Devenish

Cancer is on an exponential rise globally, and the cost of treatment is a growing international problem. South Africa alone is expected to see a 78% increase in cancer cases. Dr Alicia Sheriff, Head of the Department of Oncology, collaborated on and co-authored a research paper for the South African Medical Journal on the future of oncology treatment in the country, along with doctors from various universities across South Africa. The article, titled "The future cost of cancer: interdisciplinary cost management strategy", looks at the prognosis of cancer management in the country.

Cancer is on the rise

There is a visible growth of the cancer disease in the developing world. Rapidly changing lifestyles, uncontrolled urbanisation, pollution, and population ageing are some dynamics that provide a lethal cocktail of infectious and lifestyle risk factors that leave people at a higher risk of developing cancer.

The simultaneous increase in cancer incidence has increased the cost of treatment exponentially. The cost of cancer treatment is multitiered, making the provision of care for cancer patients a high-risk business. A combination of treatment delays, limited resources, differently skilled personnel, high patient volumes and advanced disease stage on presentation all place a bigger burden on the delivery of optimal cancer care outcomes.

Adoption of new strategies

According to the doctors, innovative thinking to embrace technology, combined with a preventive approach, as well as lowering the cost of treatment drugs should be prioritised. So should the commercialisation of new technologies that will diagnose and treat cancer in its early stages. They also encourage interdisciplinary research funding in South Africa as a way to better understand the demographic and molecular dynamics of cancer in the country, along with retaining more oncologists in the public health sector.

Efficient solutions to curb cancer mortality

The doctors assert there is a need to continue to look for more efficient measures to best treat the disease, and hopefully bring about a change in mortality levels in South Africa.

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