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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

Student receives international award in microbiology
2008-01-24

A postgraduate student at the University of the Free State (UFS) received an exceptional honour last month when he received the first prize for his presentation in the Biochemistry and Industrial Mycology session of the Asian Mycology Congress (AMC) held in Malaysia.

Desmond Ncango (24), a Ph.D. student from the Department of Microbial, Biochemical and Food Biotechnology received the first prize for his presentation on the inhibitory effects of non-steroidal anti inflammatory drugs (NSAIDs) such as aspirin on fungi.

This suggests that commonly used aspirin may be used as a cheap antifungal to combat yeast infections. Desmond also exposed novel lubricants that are used by yeasts for water-propelled movement. This may find application in nanotechnology in the lubrication of nanorobots, which are manmade miniature machines, invisible to the naked eye, which may in future be used to combat diseases such as cancer.

The conference, which was attended by more than 300 representatives from 27 countries, is a platform for mycologists (who are experts in fungi) around the world to come together and share their knowledge and research. “Many interested researchers listened to my presentation and were impressed by the novelty and scientific depth of my work,” said Desmond.

“The presentation was selected as the best because of its novelty, academic depth as well as applicability. The meticulous preparation and presentation style also contributed to the success,” said Prof. Lodewyk Kock, head of the Lipid Biotechnology Group at the department and main promoter of Desmond’s Ph.D. studies.

“I cannot really explain the feeling when my presentation was selected as the best as it was presented in a very difficult category and many senior researchers and professors also participated. I plan to use all the knowledge and skills I have learnt from Prof. Kock, who is my role model, especially to the benefit of disadvantage communities in South Africa. I want to follow an academic career at a tertiary institution when I have completed my Ph.D. studies,” said Desmond.

Desmond went to school in Botshabelo, Bloemfontein and completed his Grade 12 in 2000 with a distinction in Mathematics. He enrolled for a B.Sc. degree at the UFS, majoring in Microbiology and Physiology. After obtaining this qualification, he joined the postgraduate research group of Prof. Kock. He completed his M.Sc. degree with distinction last year and was privileged to have this research published in and on the cover of the Canadian Journal of Microbiology, a journal accredited by the Institute for Scientific Information (ISI).

He was one of six postgraduate students from the Lipid Biotechnology Group who attended the AMC conference in Malaysia. The students’ attendance was funded by the South African Fryer Oil Initiative (SAFOI), which is housed in the UFS Department of Microbial, Biochemical and Food Biotechnology. This initiative, steered by Prof. Kock, currently monitors edible oils in the food industry in South Africa and makes a quality seal available to the manufacturers and distributors of these edible oils.

“SAFOI’s income is used to fund my own research on various kinds of oils (including yeast oils) to enable postgraduate students to attend international congresses and to partially fund international scientific symposia and congresses,” said Prof. Kock.

 

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za 
24 January 2008

 

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