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05 July 2022 | Story Mandi Smallhorne
Cathedral Peak

Why mountain research matters 

“I don’t think South Africa is prepared for the possibility of a Gauteng Day Zero drought,” said Professor Francois Engelbrecht, director of the Global Change Institute at the University of the Witwatersrand. 

Professor Engelbrecht was a keynote speaker at a session of the Southern African Mountain Conference 2022, held in the Drakensberg in mid-March this year and supported by, among others, the Afromontane Research Unit at the University of the Free State (UFS). The session, hosted by international network, GEO Mountains, looked at Long-term monitoring activities and associated data availability for climate change-related applications across Africa’s mountains: status quo and next steps.

The professor went on to say we came very, very close in the 2015-2016 drought, when the Vaal Dam dropped to 25% of capacity. Had it dropped just a bit more, to 20%, the most densely populated province in South Africa, our economic hub, would have been in serious trouble, as there would have been too little water to enable pumping the last dregs into the province.

What’s the link between a Day Zero event in Gauteng and data about mountain environments?

Think of the water towers that dot the Highveld landscape in Gauteng, very visible to residents of the suburbs. Mountains can be seen as massive ‘water towers’ that provide water to people hundreds, even thousands, of kilometres from their foothills. As Dr James Thornton of GEO Mountains, co-host of the session, explained, mountains provide a flow of ecosystem services; water provision is just one of them, but it is of critical importance. “The mountains are crucial for this, due to the orographic enhancement of precipitation.” The shape and topography of mountains (their orography), forces moist air upwards into cooler air at higher elevations – an effect called ‘orographic uplift’ – so that vapour held in the air condenses into water. 

So as moisture-laden air sweeps in from the warm Indian Ocean to the east of us, it encounters the upward thrust of the long Drakensberg chain of mountains, from the Eastern Cape through Lesotho and KwaZulu-Natal and on, up to the Wolksberg Mountains in Limpopo. The upward movement of the air into colder regions triggers precipitation – rain, mist, sometimes snow.

And that moisture, falling on the soil and rocks in cool mountain air, is also less likely to evaporate and return rapidly to the atmosphere, as it might do on the coastal plains and lowlands.

The result? The most obvious consequence is waterfalls glittering in the mountain cliffs and swollen streams rushing down the slopes. Look at maps and you’ll see rivers springing from mountain sources everywhere in the world, like the Tugela heading east and the Orange flowing west from the Drakensberg in South Africa and Lesotho, or the Ganges and Indus rising in the Himalayas and the Rhine and Rhône rising in the Alps.  

Mountain water also seeps into the ground, making its way through soil and rocks and recharging the groundwater within and beyond the mountains and their foothills. This recharge of the water table from high up in the mountains also contributes to streams and rivers that supply so much of our water needs, scientists have shown.  

Mountain water in Gauteng


Gauteng residents are well aware of the role of the Vaal River in the Vaal Water Supply System, but do we understand just how much of our water originates in the Drakensberg? According to the Water Research Commission “transfers from the Maloti Drakensberg (34.4%) and the Northern Drakensberg SWSA (18.9%)” are critical to our water supply. That’s a little more than half our water in Gauteng coming from the Drakensberg.

Engelbrecht and his co-authors wrote a few years ago: “Except for the Southern Cape, the Drakensberg is the single most important source of water in Southern Africa and supplies regions where the bulk of the population resides.” (The Drakensberg Escarpment as the Great Supplier of Water to South Africa, S.J. Taylor, et al, in Developments in Earth Surface Processes Volume 21, Mountain Ice and Water, Investigations of the Hydrologic Cycle in Alpine Environments.) But, they added, due to population growth and other pressures, “In South Africa, it is now expected that demand for water will exceed supply by 2025 if nothing is done to supplement current water resources.”

That in itself is reason enough to focus on monitoring our mountains, and to support scientists observing and gathering data there. But add that to Professor Engelbrecht’s prediction that “multiyear El Nino-type droughts may plausibly occur from the mid-century (2030-2060) onwards” due to the climate change crisis, and it’s clear that we desperately need to understand the detail of how our mountains provide us with water; we urgently need to understand what is changing in the mountains.

Research matters

The ongoing and rapid changes we’re seeing in these very sensitive environments, from changing precipitation patterns, to changing land-use, to increases in population, is why we really need to “monitor and track these changes, to understand the biophysical processes and their interaction with society, and to be able to better estimate the chance, for instance, of future extreme droughts on a more local scale so we can develop measures for mitigation and adaptation,” said Dr Thornton. Better management of upstream water resources – such as the massive ‘water tower’ in the Drakensberg and elsewhere – is one tactic we should be vigorously pursuing.

There is a paucity of data about our precious mountainous areas across the world, but especially in Africa, and one of the messages of this workshop and of the conference as a whole was the importance of not just doing the monitoring and gathering of data, but making it readily accessible to all. 

Dr Susan Janse van Rensburg (of the South African Environment Observation Network or SAEON, a national facility of the National Research Foundation) spoke about the in situ environmental monitoring that is being done in important mountain areas, including Cathedral Peak, the heart of the Central Drakensberg where the conference was being held. She introduced SAEON’s new Data Portal for researchers to access and share data about mountains – and not just in South Africa, but across the whole continent. 

Omar Seidu gave a presentation on an initiative called Digital Earth Africa which collates and curates satellite data – including data on mountains. And GEO Mountains itself runs inventories which “seek to identify, link up, and make accessible existing data and information resources across the world’s mountains”.

“We’re trying to make it straightforward for researchers on the ground to make their datasets available to anybody if they choose to do so,” said Dr Thornton.

Research, observations and data-gathering on the ground (and from satellites) is the foundation for intelligent analysis, which results in solid evidence that can guide policymakers and the public to make the best choices. Mountains, our water towers, have perhaps not been enough of a focus for society in the past; information about their vital role in something as basic as water provision, and better understanding of the processes that furnish us with water, will surely help us to both mitigate and adapt to a future in which water scarcity looms so large.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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