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13 May 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Astrophysics
The Astrophysics Research Group in the UFS Department of Physics recently collaborated with the Institute of Astrophysics of Andalusia (IAA) in Spain and the University College of Dublin (UCD) in Ireland, to install a robotic telescope at the Boyden Observatory. Pictured here, are from the bottom, Teboho Rakotsoana and Simon Rakotsoana from the UFS; Emilio J Garcia from the Institute of Astrophysics of Andalusia; Prof Pieter Meintjes; and Prof Antonio M Carrillo from UCD.

The Astrophysics Research Group in the Department of Physics at the University of the Free State (UFS) is part of an international collaboration with the Institute of Astrophysics of Andalusia (IAA) in Spain and the University College of Dublin (UCD) in Ireland, which focuses on measuring the brightness of transient sources. Knowledge gained from studying these cosmic X-ray sources, which seem to appear in the sky for a short time before disappearing, will lead to a more complete and better understanding of the universe, believes Prof Pieter Meintjes, Professor of Physics and Head of the Astrophysics Programme in the Department of Physics.

To facilitate these observations, a robotic telescope network has been established, with the Boyden Observatory selected as one of the sites for BOOTES 6 (a Burst Observer and Optical Transient Exploring System).

The UFS and the IAA started working on this project more than two years ago. The foundation and pier were built through a local tender, and in January 2020, part of the dome of the structure housing the telescope arrived by ship. Due to the COVID-19 pandemic there were some delays, resulting in the crew from Spain only arriving in South Africa with the telescope and hardware in November 2021, but having to return to their country without completing the installation. They returned in April, and in early May completed assembling the telescope in collaboration with UFS researchers and technicians.

Robotic telescope opportunity to further own research

The main scientific objective of the robotic telescope is to observe and monitor the optic counterparts of gamma-ray bursts as quickly as possible when detected from space or other ground-based observatories.

Prof Meintjes says they will use the telescope to observe these transient sources that goes into an eruptive phase for a short span of time. “Since BOOTES has an enormously fast slew rate, it can start observations of erupting sources within a few seconds, which allows the Astrophysics Research Group to get data very quickly. This will certainly give us an edge over other international astronomy groups that are also involved in the same type of research,” says Prof Meintjes, the local coordinator of the project who is overseeing the whole operation locally. 

He explains the importance of monitoring these packets of enormous energy. “By observing the optical afterglow of the gamma-ray bursts, we can establish its point of origin in space. Furthermore, the shape of the optical afterglow light curve gives insight into the type of mechanism behind the gamma-ray burst, i.e., whether the burst is produced by a collision between two neutron stars or by the explosion of a hypernova event.” 

The knowledge gained with research made possible by the robotic telescope will lead to a more complete and better understanding of the universe. – Prof Peter Meintjes

The UFS Astrophysics Research Group, with its research focus on high-energy astronomy and the physics behind gamma-ray bursts, has a particular interest in this project. As the local custodians of the project and in terms of a memorandum of understanding, the group is guaranteed a certain amount of telescope time for its own in-house observation programmes.

Project expands UFS’ international research footprint

Besides the opportunity for knowledge exchange, this project establishes Bloemfontein as a region where research of international quality is being done and will help to attract talented learners to the UFS. “The successful operation of the robotic telescope may also draw more international groups to bring robotic telescopes to Boyden, thus expanding our international research footprint,” he adds. 

The fact that the Boyden Observatory is in the Southern Hemisphere and has access to the galactic centre region with its host of very interesting astronomical objects and the Magellanic Clouds, makes it a very attractive site for astronomical research,” says Prof Meintjes. 

(Dr Pat van Heerden from the UFS Department of Physics. Photo: Supplied)

“We also have a number of years of experience in robotic telescopes in the sense that we have been hosting the Watcher telescope, operated by the University College Dublin in Ireland, since 2001. Once mounted in middle May 2022, this will then be Boyden’s second robotic telescope.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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