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26 September 2022 | Story Michelle Nöthling | Photo Stephen Collett
Prof Luzelle Naude
Prof Luzelle Naudé, Professor in the Department of Psychology, delivered her inaugural lecture on the topic: In Search of Self: Emerging Adults as Actors, Agents and Authors.

How do people endeavour to answer the question: Who am I?   This is the central question that Prof Luzelle Naudé – professor in the Department of Psychology at the University of the Free State (UFS), has built her academic career on. Under the title of her inaugural lecture, In Search of Self: Emerging Adults as Actors, Agents and Authors, delivered on14 September 2022, Prof Naudé traced the arc of her academic career over the past three decades. 

Development as a Scholar

Prof Naudé started by giving an overview of her research as an early scholar, investigating students’ learning experiences and predictors of student success, followed by an exploration of the adolescence stage within the context of South Africa. Prof Naudé’s research interest then led her to investigating the third decade of life: emerging adulthood. 

Interestingly, from the turn of the century, the group of 18- to 25-year-olds take longer to transition into adulthood. This group finds themselves in an in-between space, “not being an adolescent anymore, but definitely not being an adult either,” Prof Naudé explained. This has sparked an interesting scholarly debate: is emerging adulthood indeed a new developmental stage, or is it something only applicable to a minority of Western, affluent middle-class, university students? The answer is the former. There are actually many emerging adulthoods – also among our South African youth. 

Current Research Focus

Currently, Prof Naudé is interested in the narratives of emerging adults at the intersection of self and society. The self, she pointed out, unfolds through different layers, namely the actor, the agent, and the author. “Our South African emerging adults are acting in an increasingly complex and transitioning social world. As agents, they advance through this complexity by telling redemptive stories of generativity, upward mobility, and of liberation. And as authors, they reconstruct their past, present, and future into a coherent life story and a narrative identity,” Prof Naudé said.

Naude Inaugural From the left; Dr Edwin du Plessis, Head of Department of Psychology; Prof Heidi Hudson, Dean of the Faculty of The Humanities; Prof Luzelle Naudé , and Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation. Photo: Stephen Collett. 

The Way Forward

“I’ve became convinced,” Prof Naudé emphasised, “about South Africa and the Global South’s ability to contribute to global knowledge production.” Prof Naudé and her team are therefore adding a South African voice to several multicultural, multinational projects, including the African Long-Life Study – in collaboration with the University of Zurich – and the Selves within Selves project. Prof Naudé’s vision, however, is to ultimately establish an Identity Research Hub at the UFS to consolidate research activities in this field and to formalise interdisciplinary partnerships.

Watch recording video below:





News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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