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26 September 2022 | Story Michelle Nöthling | Photo Stephen Collett
Prof Luzelle Naude
Prof Luzelle Naudé, Professor in the Department of Psychology, delivered her inaugural lecture on the topic: In Search of Self: Emerging Adults as Actors, Agents and Authors.

How do people endeavour to answer the question: Who am I?   This is the central question that Prof Luzelle Naudé – professor in the Department of Psychology at the University of the Free State (UFS), has built her academic career on. Under the title of her inaugural lecture, In Search of Self: Emerging Adults as Actors, Agents and Authors, delivered on14 September 2022, Prof Naudé traced the arc of her academic career over the past three decades. 

Development as a Scholar

Prof Naudé started by giving an overview of her research as an early scholar, investigating students’ learning experiences and predictors of student success, followed by an exploration of the adolescence stage within the context of South Africa. Prof Naudé’s research interest then led her to investigating the third decade of life: emerging adulthood. 

Interestingly, from the turn of the century, the group of 18- to 25-year-olds take longer to transition into adulthood. This group finds themselves in an in-between space, “not being an adolescent anymore, but definitely not being an adult either,” Prof Naudé explained. This has sparked an interesting scholarly debate: is emerging adulthood indeed a new developmental stage, or is it something only applicable to a minority of Western, affluent middle-class, university students? The answer is the former. There are actually many emerging adulthoods – also among our South African youth. 

Current Research Focus

Currently, Prof Naudé is interested in the narratives of emerging adults at the intersection of self and society. The self, she pointed out, unfolds through different layers, namely the actor, the agent, and the author. “Our South African emerging adults are acting in an increasingly complex and transitioning social world. As agents, they advance through this complexity by telling redemptive stories of generativity, upward mobility, and of liberation. And as authors, they reconstruct their past, present, and future into a coherent life story and a narrative identity,” Prof Naudé said.

Naude Inaugural From the left; Dr Edwin du Plessis, Head of Department of Psychology; Prof Heidi Hudson, Dean of the Faculty of The Humanities; Prof Luzelle Naudé , and Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation. Photo: Stephen Collett. 

The Way Forward

“I’ve became convinced,” Prof Naudé emphasised, “about South Africa and the Global South’s ability to contribute to global knowledge production.” Prof Naudé and her team are therefore adding a South African voice to several multicultural, multinational projects, including the African Long-Life Study – in collaboration with the University of Zurich – and the Selves within Selves project. Prof Naudé’s vision, however, is to ultimately establish an Identity Research Hub at the UFS to consolidate research activities in this field and to formalise interdisciplinary partnerships.

Watch recording video below:





News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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