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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.

There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

Kovsies blossom with potential
2010-02-04

Pictured with Prof Jansen are, from the left: Marike Botha, Sibusiso Tshabalala, Cumine de Villiers, Portia Lehasa and Meyer Joubert.
Photo: Hannes Pieterse


The Rector and Vice-Chancellor of the University of the Free State (UFS), Prof. Jonathan Jansen, recently made closer acquaintance with five top Grade 12 achievers who are currently first-year students at the UFS.

The five students all achieved exceptional results in their final exams.

Cumine de Villiers from the Volkskool Secondary School in Potchefstroom obtained seven distinctions. She is an MBChB I student and resides in Roosmaryn Residence on the Main Campus. People are her passion, which makes a career as a doctor ideal for her. “I can help people physically, as well as emotionally. And save lives!” Her advice to learners is to work hard from Grade 11 already. According to her a balanced life is also very important: “The more you do, the better you can do.” One of her goals is to learn Sesotho while she is studying.

Marike Botha attended Potchefstroom Gymnasium. She obtained seven distinctions. She is also studying MBChB I and plans to become a paediatric surgeon. “I know one is going to lose patients, but one will also save lives.”

She resides in Roosmaryn Residence and plans to enjoy her student life to the full: “I am going to attend everything! Every dance, rugby match and serenade – there are some things in life that one can only experience once, and one’s first year is one of those.” According to her, the Grade 12 work is not that difficult; it is only a lot. She advises matriculants to always to their best and never to leave anything till later.

Sibusiso Tshabalala from HTS Welkom obtained three distinctions. He is studying BCom Law. He chose that degree because it perfectly integrates law and commerce. “In that way I am keeping my career options open”. He chose Kovsies for the opportunity to be part of one of the best Faculties of Law in South Africa. He resides in JBM Hertzog Residence. His advice to matriculants is to fully make use of every opportunity. “There will be setbacks – it is not supposed to be easy. All of that makes you a stronger person. Strive after your own goals – don’t measure them against others’ goals.”

Portia Lehasa from Eunice High School obtained five distinctions. She is studying BA Accounting and resides in Roosmaryn Residence. She chose Kovsies in order to be part of the transformation.

“Transformation leads to growth – and growth is essential for all persons.” She chose accounting because she enjoys challenges. “It is also a skill that will enable me to empower the economic status of South Africa.”

She also wants to become involved in everything on campus and make a difference. “You are going to see me a lot – I am going to change the world!” She also has some advice for matriculants: “It is very important to have a goal. In that way one still has something to strive for. It helps incredibly.”

Meyer Joubert attended the Ferdinand Postma Secondary School in Potchefstroom. He obtained seven distinctions. He is an MBChB I student and resides in Abraham Fischer Residence. “One’s life only becomes meaningful once one does something for someone else; that is why I want to become a doctor. By means of medicine one can make a difference to someone else’s life.” He plans to become the best doctor possible. According to him learners can take it leisurely up to Grade 10. “The requirements for many fields of study, like medicine, already apply from Grade 10. Therefore it is important to start to focus and work hard from then onwards. However, don’t only study! Balance is very important; therefore participate in sports, cultural activities and, of course, socialise.”

Prof. Jansen was, rightly so, impressed by all the talent that have settled at Kovsies this year: “This is only the beginning. With so much potential Kovsies can blossom!”

Media Release:
Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
4 February 2010
 

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