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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.

There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

Postgraduate School opens at UFS
2011-05-19

 
Prof. Maresi Nerad, from Washington university in Seattle, USA
Photo: Stephen Collett

We are celebrating the launch of our new Postgraduate School (PGS) on our Main Campus in Bloemfontein from 16 - 20 May 2011.

In line with national priorities for research-based postgraduate education and the focus of the UFS Academic Turnaround Strategy, the aims of the Postgraduate School are to:

  • improve the quality of postgraduate student research;
  • produce graduates who are global citizens, research literate and able to reflect ethically on the purpose, process and product of research;
  • improve throughput rates of postgraduate students; and
  • make the experience of being a postgraduate at the UFS one which is stimulating, enjoyable and which contributes to the development of the person beyond the limits of her or his discipline(s).

“We hope that the school will be a pleasant place to pursue research scholarship, discuss ideas and relax, and we look forward to welcoming postgraduates and other scholars to the school,” Prof. Neil Roos, Director of the UFS Postgraduate School said.

This significant event in the academic transformation of the university goes hand in hand with the inaugural lecture of Prof. Maresi Nerad. Prof. Nerad’s impressive CV reads amongst others that she has a M.A. (Political Science) at the Technical University of Darmstadt, Germany and a Ph.D. (Higher Education) at the University of California, Berkeley. She is also the founding director of the national Center for Innovation and Research Graduate Education (CIRGE).

As Professor Extraordinary in the UFS’s Postgraduate School, she is bringing more to the table than a world of wisdom and her passion for the postgraduate education. “I can contribute lessons learned from four distinct professional experiences, including 17 years of administrative and scholarly leadership in undertaking the conceptual and practical transformational work of organisational change at two US postgraduate schools, where I worked amongst others to improve the quality of mentoring, shorten the time to doctoral degree, and improve doctoral completion rates.”

She also brings to the UFS her experience as founding and current director of the first research center for studies on graduate education in the world. “It is our mission to discover how best to prepare Ph.D. students to be effective leaders in research and society,” she said.

Prof. Nerad says that she is committed to support and consult with the UFS Postgraduate School. She would particularly encourage the use of research to understand postgraduate education in all its dimensions at the UFS better and to use the evidence-based findings as a base for policy-making and resource allocation.

In reflecting on her vision for the UFS Postgraduate School, Prof. Nerad says that five years from now she hopes to see the UFS having strengthened its position as a major driving force in the national South African postgraduate-education community for internationalising postgraduate education. She is also confident that the UFS will supply increased numbers of skilled postgraduates who are “intellectual entrepreneurs and risk takers with a social consciousness, who have sustainability of the systems of the planet as a core value”.

“Five years from now the PSG will have taken the lead in preparing graduate students who are world citizens,” Prof. Nerad concluded.

 

Presentation on PhD students reveals more than meets the eye

British professor presents a discussion at UFS

Journey from student to scholar

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Female academics talk about joys and lessons

Research plus the internet equals the cyber scholar
 


 

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