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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.

There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

In her inaugural lecture, Prof Helene Strauss explores symbols that reflect our history
2014-02-18

 

Prof Helene Strauss
The burning tyre – image of promise and disappointment
Photo: Stephen Collett

Prof Helene Strauss did not disappoint in her highly-anticipated inaugural lecture “The Spectacles of Promise and Disappointment: Political Emotion and Quotidian Aesthetics in Post-transitional South Africa”. She posed some very challenging ideas on the promises and disappointments that arouse from apartheid. Prof Strauss pointed to the fact that “… a promise must promise to be kept; that is, not to remain spiritual or abstract, but to produce events, new effective forms of action, practice, organisation, and so forth.”

She underscored the message of her lecture by making use of the image of a burning tyre – a symbol commonly associated with apartheid. This act of ‘necklacing’ is closely connected to the violence and protests of that era. Prof Strauss used this image to represent an array of social concerns: global mass protest, modernity and mobility, waste economies and waste management, environmental destruction, as well as poverty and resistance in varied formats.

Some of South Africa’s greatest artists have used the burning tyre in their work, particularlyBerni Searle and Zanele Muhloi. Not only does it trigger the shadow of the damaging past, but “more recently, it has come to figure also in the spectacles of promise and disappointment that have marked the country’s transitional and post-transitional periods,” Prof Strauss remarked.

Prof Strauss focuses her research on these symbolisms in our history because of “the questions that they raise about the emotional cultures produced in the aftermath of apartheid and for the unique contribution that they make to current debates on political and aesthetic activism.”Her passion for this subject comes from the “affective or emotional legacies of various forms of structural inequality, an interest that owes a sizeable debt to postcolonial, queer and feminist critical theory and creative work of the past hundred or so years.”

Prof Strauss accepted a position at the University of the Free Sate in 2011 and currently works in the Department of English. She is part of the Vice-Chancellor’s Prestige Scholars Programme and holds a PhD from the University of Western Ontario. Previously, she held the position of Assistant Professor in the Department of English and Cultural Studies at McMaster University in Canada, where she resided for 11 years.

Among the guests were Prof Jonathan Jansen, Profs Botes and Witthuhn, lecturers in the Department of English, members of the Faculty of the Humanities, students and some of Prof Strauss’ colleagues from Canada.

 

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