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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.
There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

IRSJ marks five years of championing social justice
2016-08-12

Description: IRSJ 5 year Tags: IRSJ 5 year

Members of the Advisory Board of the IRSJ,
Prof Michalinos Zembylas (Open University
of Cyprus), Prof Shirley Anne Tate (Leeds
University, England), and Prof Relebohile
Moletsane (University of KwaZulu-Natal),
listen to a speaker on the programme.
 Photo: Lihlumelo Toyana

The Institute for Reconciliation and Social Justice (IRSJ) marked its fifth anniversary with a function on 27 July 2016 in the Reitz Hall of the Centenary Complex on the Bloemfontein Campus of the University of the Free State (UFS). Earlier that day, the Advisory Board of the IRSJ, chaired by Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, hosted their annual meeting.

A new book was also launched, co-authored by JC van der Merwe, Deputy-Director at the IRSJ and Dionne van Reenen, researcher and PhD candidate at the IRSJ. It is entitled Transformation and Legitimation in Post-apartheid Universities: Reading Discourses from ‘Reitz’. The function featured not only reflections on the IRSJ, but a four-member panel discussion of the book and higher education in 2016.

The IRSJ came into being officially at the UFS in January 2011. Prof André Keet, Director of the IRSJ, said: “With a flexibility and trust not easily found in the higher education sector, the university management gave us the latitude and support to fashion an outfit that responds to social life within and outside the borders of the university, locally and globally.”

The IRSJ has not hesitated to be bold and
courageous in reforming ... traditional policies."

 

Prof Jansen went on to mention three things he finds appealing about the IRSJ: “Thanks to Prof Keet and his team’s vision and understanding of how important it is for students to have a space in which they can learn how to be, learn how to think, and learn how to contribute, the IRSJ has become a place where students can learn about things that they might not learn in the classroom. Second, it created, for the first time, a space where members of the LGBTIQ community could gather in one place. And third, it speaks to the intellectual life of the university, as evidenced by the research and publications produced over the past few years.”

Prof Jansen added: “The IRSJ will only be successful to the extent that we have safe spaces, courageous spaces, in which not only black students talk to themselves, but where black and white students talk together about their difficulties. If you’re entangled, you can’t get out of [that] unless you speak to the other person.”

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Prof Michalinos Zembylas of the Open University of Cyprus and member of the Advisory Board, said of the IRSJ: “The works produced by the institute in this short time have been valuable to this community and beyond, because they recognise the complexities of education, ... while pushing the boundaries of how to translate theoretical discussions into practical, everyday conditions. ... For example, the IRSJ has not hesitated to be bold and courageous in reforming some traditional policies in this university—remnants of an ambivalent past that reproduced inequality and disadvantage.

In reflecting on how the IRSJ came into being during her opening remarks, Dr Lis Lange, Vice-Rector: Academic at the UFS, said that it has always been “dedicated to transformation.” She added that it “gathered the energy and creativity of some of our most promising student leaders.” She concluded: “For me, the greatest success of the Institute, besides publications and local and international networks, is the fact that something that started in the margins is being asked today to come closer to the centre, to play a larger role in the structural transformation of the university.”

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