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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.

There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

Innovation the focus of 28th Sophia Gray Memorial Lecture
2016-09-06

Description: Stratford furniture design Tags: Stratford furniture design

Stratford never lost his passion for designing
furniture. Pictured here is some of his furniture
exhibited at the Oliewenhuis Art Museum.
Photo: Francois van Vuuren: iFlair Photography

Al Stratford, designer, inventor and architect, presented the 28th Sophia Gray Memorial Lecture on 25 August at the Reservoir at the Oliewenhuis Art Museum in Bloemfontein. The event, hosted by the Department of Architecture at the University of the Free State, was also the opening of an exhibition of Stratford’s work.

In his career of 40 years, Stratford has patented many products and won several awards in industrial design and architecture. He is known in South Africa for his development of innovative building technology such as the Winblok Precast Concrete Window System. In 2009 and 2010, he also served as president of the South African Institute of Architects.

The title of his lecture was: Reductive Innovation in Architecture. Throughout his career, Stratford endeavoured – through his designs and inventions – to apply the principle of “reduction” to the building material he used and technology he examined.

Stratford designs and builds smart buildings
Stratford says a home is the paradigm of self-expression. His career as architect started with the building of five houses in Gonubie, near East London. Everything he knew about architecture at that stage, he had taught himself by reading on the subject at the local library. Later on, he achieved great heights in his career by designing and building, among others, the Stratford Guesthouse; the sustainable and resourcefully designed campus buildings for the University of Fort Hare (an institutional building not utilising any electrical air-conditioning); the Edenvale Baptist Church; and a community hall.

His technology is widely used in the building industry

“The arrogance in me gets humiliated when I
see what other people and God has done.”


His technical drawing skills, acquired at an early age during his training as motor mechanic, are still practised years later, particularly in his inventions. Stratford is the inventor of technology commonly used in the building industry today. Of these, the Winblok window system which he patented in 1981, is one of his best known patents. The use of these windows is characteristic of many of the buildings he designed and built. Other technology he invented and patented, includes the Winstep stairs, the Windeck flooring system, and the StratFlex furniture technology.

Furniture designs win him awards
He likes to quote architect Ludwig Mies van der Rohe: “A chair is a very difficult object. A skyscraper is easier.” Stratford started designing and manufacturing his own furniture and never lost this passion. In 2013, he won the Innovation Award at the Design Indaba for his “flat pack” furniture technology.

The humble Stratford – designer, inventor, industrialist, and architect – says he is simply playing around with God’s creation. “The arrogance in me gets humiliated when I see what other people and God has done.”

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