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15 September 2022 | Story André Damons | Photo André Damons
Dr Osayande Evbuomwan, Prof Willy Vangu and Dr Gerrit Engelbrecht
Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, left, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, right, with Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, after his lecture.

There is no doubt that an institution like the University of the Free State (UFS), with its calibre and pedigree, needs a PET/CT machine (medical-imaging device that simultaneously and clearly reveals both anatomical details and metabolic processes within the body), particular in oncology, in improving the management of patients. 

This is according to Prof Willy Vangu, Chief Specialist and Head of Nuclear Medicine at the University of the Witwatersrand, who was a guest lecturer on 8 September 2022 at the Department of Nuclear Medicine at the UFS.

Positron emission tomography (PET) is a type of nuclear medicine imaging modality that measures the metabolic activity of the cells of body tissues. PET imaging is useful in the evaluation of patients with neurological, cardiac, infection, inflammation, and most importantly oncological conditions. Through its ability to detect metabolic changes very early, it can detect disease conditions that might not be easily detected on other forms of anatomical imaging.

Role of PET/CT in different clinical scenarios

In his lecture, Prof Vangu talked about the role of PET/CT in different clinical scenarios. By giving practical examples, he explained the role of PET/CT in different aspects of clinical medicine, including brain imaging for dementia, movement disorder and cerebrovascular reserve. 

“Looking at dementia, we will focus on one of diseases that is today becoming a major source of health concern, Alzheimer's disease. The latest Alzheimer's report that was published in 2018 stated that there are 50 million individuals currently suffering from Alzheimer's. They forecast that in 30 years we are going to have more than 150 million people suffering from this disease. PET/CT imaging can identify very early the typical patterns associated with all the different types of dementias, including Alzheimer's disease…”

For cardiac application, Prof Vangu said there are so many indications for PET/CT in cardiac imaging. One of the most important is the assessment of myocardial viability, in patients who have suffered from cardiomyopathy due to ischemic heart disease. PET/CT offers a noninvasive method of identifying viable myocardium that would benefit from revascularisation, with a very high diagnostic accuracy. 

Prof Vangu, who is also the head of nuclear medicine at the Charlotte Maxeke Johannesburg Academic and Chris Hani Baragwanath hospitals as well as head of the department for radiation sciences at the University of the Witwatersrand, said PET has been around for many years and is not something new. However, in clinical practice, PET imaging became significant with a breakthrough that occurred with the production of the glucose analogue tracer, 18F-fluorodeoxyglucose (FDG). This tracer in PET/CT imaging has revolutionised the management of cancer patients for the oncologist. It offers the ability of more accurate cancer staging, assessment of treatment response, assessment of disease recurrence and in some situations, surveillance. It has the ability to predict early which cancer patients will benefit from a particular drug, thereby giving the oncologist an idea on either to de-escalate treatment or change to a second line regimen very early on in the management. 

PET-CT scan imaging machine

An internet example of an image taken by a PET/CT machine. Photo for illustration: A PET/CT Imaging machine.


PET/CT came onto the market only in the year 2001, when it was launched for the first time by David Townsend (a physicist) and Ronald Nutt (electrical engineer). As at today, almost every institution in the country has at least one PET/CT machine.


“Looking at clinical applications, which is really the crux of the lecture today, there are so many clinical applications to talk about. You need a full week of a PET/CT symposium to go through all of them (and) maybe that might not even be enough. We can at least from this talk have an idea on how PET/CT can be applied in clinical medicine,” said Prof Vangu.

No other road for the university but to get a PET/CT machine

He also showed the impact and results that PET/CT imaging had in the management of infection and inflammation including TB. He said the role of PET/CT in TB is for monitoring of treatment, identification of extrapulmonary TB and prognosis. 

In concluding his lecture, he said there is no other road for the university but to get a PET/CT machine. “There is no argument about it. The institution needs it to improve the management of patients, especially the oncology and cardiology patients. Confidently making the decision on which patients to treat, how to treat them, identifying and evaluating their true response to therapy requires a PET/CT machine.

“I am happy to hear that the policy- and decisions-makers in the province and the university are looking forward to having a PET/CT machine,” he said later. 

Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer, and Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, are both looking forward of having a PET/CT in the department because in addition to its use in clinical setting, it has a huge role to play in research and training postgraduate students, as PET/CT imaging makes up a huge chunk of the postgraduate training curriculum

News Archive

The influence of load shedding on the evening timetable
2008-01-31

The load shedding that is being applied at present also has a certain influence on especially the evening module and venue timetable. As part of the contingency planning of the UFS, an alternative module and venue timetable has been compiled so that classes that cannot take place during evenings in the week as a result of load shedding can be accommodated on Fridays and Saturdays.

After consultation with students, lecturers will decide whether the alternative timetable will apply when load shedding does indeed occur or whether the alternative timetable will be a permanent arrangement.

The alternative evening module and venue timetable are as follows:

Classes that are presented in the timeslot 18:10 to 21:00 on Thursdays are alternatively accommodated in the same venues at the same times on a Friday. Double or more periods that commence at 17:00, but continue into the period of load shedding are also included in this alternative arrangement.

It is important to note that lecturers who present double periods that start at 14:10 and continue into the period of load shedding must make ad hoc arrangements should they wish to have their periods also included in the alternative timetable.

Classes that take place in the timeslot 20:10 to 22:00 on Wednesdays are alternatively accommodated in the timeslot 08:10 to 12:00 on Saturdays, in a few cases in different venues from those scheduled initially. Double or more periods that start at 18:10, but continue into the period of load shedding are also included in this alternative arrangement.

The venue changes for Wednesday periods that are accommodated on Saturdays are as follows:

  • BLG114 Practical 1 English (A) in the Biology Building 28 from 08:10 to 11:00
     
  • STK114 Practical 1 Afrikaans (D) in West Block 201 from 09:10 to 11:00
     
  • STK114 Practical 1 English (D) in West Block 202 from 09:10 to 11:00
     
  • ALM108 Lecture 1 English (G) in FGG169 from 09:10 to 11:00
     
  • EKN314 Lecture 2 English (A) in the Rindl Hall from 09:10 to 11:00
     
  • EFA112 Lecture 2 Afrikaans (A) in FGG377 from 10:10 to 11:00
     
  • EFK112 Lecture 2 Afrikaans (A) in FGG183 from 10:10 to 11:00
     
  • DLS112 Lecture 2 English (A) in FGG184 from 10:10 to 11:00
     
  • ALC108 Lecture 2 English (E) in the South Block 1 from 10:10 to 11:00
     
  • DLS112 Lecture 2 Afrikaans (A) in the FGG377 from 11:10 to 12:00
     
  • EFA112 Lecture 2 English (A) in FGG183 from 11:10 to 12:00
     
  • EFK112 Lecture 2 English (A) in FGG184 from 11:10 to 12:00
     
  • ELF112 Lecture 2 English (A) in FGG169 from 11:10 to 12:00
     
  • EKN214 Lecture 3 English (A) in Stabilis 4 from 11:10 to 12:00

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