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21 April 2023 | Story Leonie Bolleurs | Photo Supplied
Striving to make a difference in the field of biodiversity conservation, Dr Katlego Mashiane decided to pursue a PhD in Geography, focusing on the spatial modelling of grassland diversity and nutrients in subalpine environments. He received his PhD during the recent April graduation ceremonies on the Qwaqwa Campus.

In the small village of Ga-Mabotia about 25 km outside of Polokwane, Dr Katlego Mashiane grew up, surrounded by rocky mountains characterised by boulder outcrops, where he interacted with nature from an early age. 

He recently obtained his PhD, majoring in Geography, from the University of the Free State (UFS), which was conferred on him during the April graduation ceremonies that took place on the UFS Qwaqwa Campus. The title of his dissertation is Grass nutrients estimation as an Indicator of rangeland quality using satellite remote.

Predicting the presence of biodiversity and nutrients in an area

Based on the principle that diverse grasslands tend to perform better, environmental changes threaten the resilience and services these grassland ecosystems provide. The study examined how many different types of plants and animals can be found at a particular place to enhance our understanding of the ecosystem’s value to humans, and that biodiversity loss will reduce these ecosystem services. Focusing on spatial modelling of grassland diversity, Dr Mashiane specifically investigated the influence of topography and remotely sensed satellite data on species richness and diversity in subalpine environments, and how they are affected by the availability of grass species. To determine this, he used a random forest machine-learning algorithm to find the best information in the data that could be used to estimate the levels of species richness, diversity, and nitrogen in a protected national conservation park. 

His study discovered that some data types – such as the near-infrared variable and certain vegetation data (EVI and SAVI) – were especially useful for determining the number and variety of species in a certain area. With this information, scientists can create models that predict the presence of different types of biodiversity and nutrients in an area.

Playing a key role in protecting our natural assets

Equipped with this knowledge, one will be able to understand how to protect and preserve different types of biodiversity and promote the nutritional value of both plants and animals in the environment. “Land managers could use this information for conservation strategies,” states Dr Mashiane, who decided to pursue this study because he was curious about how environmental changes will affect species.

“Grasslands provide important ecosystem services underpinning human well-being, and therefore warrant our protection; I would like to play a role in protecting our natural assets and contribute to understanding our biomes, especially in the context of global change,” he says.

In the next five years, Dr Mashiane plans to pursue further research and mentor other students in his field of study.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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