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26 April 2023 | Story Leonie Bolleurs | Photo Leonie Bolleurs
reusable sanitary pads
A team of researchers from the UFS is part of a project to invent a reusable sanitary pad that is safe, hygienic, comfortable, easy to use, and friendly to the environment. From left are: Prof Katinka de Wet, Dr Marietjie Schutte-Smith, Prof Deon Visser, and Prof Lizette Erasmus.

A new reusable sanitary pad (RSP) will bring relief to many women during their menstrual cycle.

Dr Marietjie Schutte-Smith, Senior Lecturer in the University of the Free State (UFS) Department of Chemistry, together with Prof Deon Visser, Head of the Department of Chemistry, and Prof Lizette Erasmus, Associate Professor in the same department, are leading a diverse team that decided 18 months ago to do something about the challenge of not having access to conventional sanitary ware and water due to poverty and infrastructure challenges – a challenge many young women in South Africa face every month.

The team included Prof Katinka de Wet, Associate Professor in the Department of Sociology, in this process in an effort to gain a better understanding of the current perceptions, experiences, and preferences of those who will ultimately use these sanitary products. 

“We wanted to do research that has a direct and tangible impact on our immediate society,” says Prof Erasmus. 

New technology

The research team turned their focus to reusable sanitary pads (RSPs), specifically the invention of a product that can be cleaned without being exposed to direct sunlight. 

Dr Schutte-Smith explains that most RSPs must be exposed to direct sunlight to dry and prevent bacterial growth. “Exposing RSPs to sunlight is challenging for users residing in densely populated areas, besides the fact that many people find the public display of sanitary products embarrassing.”

She believes a product that can be washed and left indoors to dry, one that has antibacterial and antimicrobial properties under normal light conditions, and with durable superabsorbent inner layers, could alleviate some of these challenges.

The team then started working on technology including nanoparticles (NPs) that affix to textiles and will kill germs and fungi when exposed to normal light. 

Prof Erasmus says, “Attaching NPs to materials is not a new concept, however, the use of nanoparticles that are activated by normal light conditions is new… Also, we have synthesised several absorbent materials using natural fibres and biopolymers as the main constituents. This is an ongoing process to enhance their absorbent properties and durability so that they can be included in our product.”
We wanted to do research that has a direct and tangible impact on our immediate society. – Prof Lizette Erasmus

She adds that when the RSPs are eventually discarded (after four to five years) they will break down in the environment and not contribute further to the plastic waste problem the world is facing. Most disposable sanitary pads (DSPs) are not environmentally friendly and take 500 to 800 years to decompose. 

Dr Schutte-Smith goes on to explain that the sanitary ware will be manufactured by sewing different layers together. “The outer lower layer will consist of a hydrophobic (fluid-repellent) layer to prevent leaking, and the inner layer will consist of the synthesised and biodegradable superabsorbent polymer (SAP).”

The product will be mixed into cotton and will be removable (for better cleaning). “It will also contain NPs that use natural indoor light to disinfect. The top layer also contains our nanotechnology and will relay fluids to the absorbent inner layer.”

Social implications

Besides the important work being done by chemists to incorporate technology that will ensure the product makes sense scientifically, it is also important that the experiences, perceptions, and ideas of end users are kept in mind. 

Prof De Wet says social scientists were included in the design and development of this product to ensure that the actual needs of the end users are taken into consideration. The idea is to collaborate with school learners and university students to get their feedback on the development and eventual use of these newly developed RSPs.

“The aim, therefore, is to sensitise menstruating individuals as to the possible personal advantages of using reusable sanitary pads, including that it is less expensive in the long run, thus eliminating the problem of access to quality and reliable sanitary ware. There could even be some potential health advantages to using such products, as current disposable products contain phthalates that have been shown to have adverse health effects on individuals,” she states.

Prof De Wet also points out the environmental benefits of using reusable sanitary products, and the importance of sensitising young people to the environmental costs of single-use plastic consumption, of which sanitary ware is a major contributor. “Environmental consciousness is part of the social side of the project, given the pressures globally on the human-induced impact on our planet, and its devastating consequences,” she says. “We want the science (chemistry) to have a real social impact in people’s lives individually, socially, and environmentally.”

Future steps

According to Prof Visser, the team already has a prototype in place, which now needs to be perfected through inputs from end users. They hope to have an industry partner within the next six months that will help to get this product on the market.  

The team of chemists worked hard to develop a product that will have the potential to change many lives for the better, allowing young girls and women to thrive in life. 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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