Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
27 June 2023 | Story Department of Communication and Marketing | Photo Charl Devenish
Dr Abraham Matamanda and Prof Lochner Marais
UFS researchers, Dr Abraham R Matamanda, Senior Lecturer in the Department of Geography, and Prof Lochner Marais, Head of the UFS Centre for Development Support, collaborated with researchers in the UK and Brazil on a study on the impact of COVID-19 on children and young people. The study is part of the international PANEX-Youth research project.

Researchers from South Africa, the UK, and Brazil recently conducted a study on the impact of COVID-19 on children and young people, particularly those from disadvantaged households. Their research highlights that the pandemic has deepened existing inequalities, with children and young people’s voices and needs not being considered in policy decisions.

The study conducted by researchers from the University of the Free State (UFS) and the University of Fort Hare in South Africa; the University College London, the University of Birmingham, and Nottingham Trent University in the UK; and the University of São Paulo in Brazil, found that pandemic policy decisions largely ignored young people’s needs, resulting in long-term losses.

Educational inequalities

The report, titled International and National Overviews of the impact of COVID-19 on Education, Food and Play/Leisure and Related Adaptations, outlines how slow government action and policy gaps in efforts to stop the spread of COVID-19 have had a negative impact on children and young people’s health and welfare.

South Africa has been one of the countries hardest hit by COVID-19, and the study shows that due to social isolation and economic disruption caused by lockdowns, children and young people’s education has been stunted, their access to nutritious food has been reduced, and their ability to develop socially through play has been significantly restricted. The impact was worst for those living in disadvantaged poor households.

The study, which is part of the first stage of the PANEX-Youth research project, is divided into two volumes: the ‘Long Report’, highlighting the wider impact of the pandemic on children across the world, while the ‘Short Report’ drills down on the impact on three countries, namely the UK, South Africa, and Brazil.

Further insights from the study show that the digital divide has compounded educational inequalities as education has moved online during the pandemic, with households and regions with insufficient internet access falling behind. Collectively, and combined with the continuing cost-of-living crisis, the researchers believe that these disadvantages are likely to have detrimental consequences for children and young people in the short and long term, with many not yet visible.

Future pandemic planning

The team – which includes UFS researchers, Dr Abraham R Matamanda, Senior Lecturer in the Department of Geography, and Prof Lochner Marais, Head of the UFS Centre for Development Support – expects that policy gaps during the pandemic will negatively impact young people’s professional life trajectories, healthy lifestyles, mental well-being, educational opportunities, and self-confidence.

The team put together five recommendations to ensure that children’s well-being is incorporated into any future pandemic planning. These suggestions include:

  • The need to keep children and young people at the centre of pandemic preparedness efforts.
  • More priority and attention given to the hidden voices and experiences of young people, and particularly those from monetary poor households.
  • Greater recognition that schools play an important, central role as life and care hubs.
  • Greater recognition of play and leisure as rights that are fundamental to children and young people’s development.
  • More structured and systemic responses to multiple dimensions of risk from local and national responses are recommended, based on a rigorous assessment of what worked and failed during the pandemic.

Adapting in the post-pandemic period

Prof Lauren Andres, Professor of Planning and Urban Transformations at the University College London – also the lead author of the report – said: “COVID-19 exposed and exacerbated inequalities that already existed prior to the pandemic. Children and young people’s voices and needs were not heard and accounted for. Our research shows that because of policy gaps and slow government action during the pandemic, disadvantaged children and young people are now facing serious consequences that could be with them for a long time, both here in the UK and around the world.”

According to Dr Matamanda, “The COVID-19 pandemic showed the lack of understanding of what children and young people need in their daily lives. During the pandemic, the rights of children and young people, especially play/leisure, accessing adequate food and education, seemed to be overlooked or least prioritised. This was evident from the slow and inconsistent COVID-19 government policies and strategies that failed to acknowledge the networks and value chains through which children and young people are supported. In this way, our research shows the gaps and inequalities created and widened among children and young people in South Africa, especially those from disadvantaged households who have now been left behind and are grappling to adapt in the post-pandemic period.”

Read the full report here: https://panexyouth.com/

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept