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Eradicating gender-based violence

13 June 2023 | Story Valentino Ndaba | Photo Supplied

GBV UFS Values — Values are a powerful tool in the fight against gender-based violence.

Dr Choice Makhetha, a participant in a recent dialogue focused on the role of student leadership in eradicating gender-based violence (GBV), conveyed a pivotal message during her opening statement. She emphasised universities’ dedication to reshaping and instilling new values in the lives of students. This sentiment laid the foundation for an insightful discussion centred on the importance of values in combating GBV.

"In university, we work hard to reshape and bring new values into students' lives,” said the Director of Student Affairs at Stellenbosch University, who is a former University of the Free State (UFS) Vice-Rector: External Relations, Dean of Student Affairs, and alumna.

The dialogue was a collaborative effort between the Gender Equality and Anti-Discrimination Office and the Division of Student Affairs. It featured esteemed experts in student governance and leadership, including Sikhululekile Luwaca, Assistant Researcher in the UFS Unit for Institutional Change and Social Justice, Prof Nicky Morgan, former UFS Vice-Rector: Operations, and Moema Motlogelwa, Assistant Director in Student Affairs.

The importance of being value-driven

Luwaca emphasised the need for student leaders to contemplate UFS values. He remarked, "Vision 130 commits us to be accountable. It affirms that those within the UFS will be held accountable. We are devoted to creating an environment that fosters exceptional teaching, learning, and scholarship, as well as caring for ourselves, our fellow human beings, and the natural environment. Our commitment lies in advancing the values of human dignity through ethical and transparent conduct, along with institutional responsibility."

In addition, Luwaca proposed the implementation of a prerequisite course on GBV for all students aspiring to hold positions in the Student Representative Council. This measure would further enhance awareness and understanding of GBV among future leaders.

Echoing similar sentiments, Prof Morgan advocated for justice and respect as fundamental guiding principles in all interactions. “Develop an internal compass of what is right – and that does not depend on laws, politics, or democracy. GBV among our leaders is not a political issue.”

With great power comes great responsibility

Motlogelwa's contribution focused on developing student leaders and addressing gender-based violence (GBV). He highlighted three key steps: awareness and education, advocacy and support, and strengthening partnerships. He emphasised the need for well-informed student leaders who understand university policies and referral systems. Motlogelwa also stressed the importance of advocating and supporting GBV prevention. Additionally, he proposed collaborative efforts with relevant entities to achieve common goals. Ultimately, the goal is to produce model citizens who embody the university's vision and values.

What values do we subscribe to as an institution?

At the UFS, our values are integral to shaping our culture and guiding our actions and choices. These values include a commitment to excellence, innovation, and impact, as well as accountability, care, and social justice. These principles are articulated in Vision 130, our strategic intent to reposition the institution by the time of its 130th anniversary in 2034.

News Archive

UFS study on cell development in top international science journal

2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
18 September 2008

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