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21 June 2023 | Story Sanchay Kalicharan | Photo Supplied
Sanchay Kalicharan
Sanchay Kalicharan, ETDP SETA Intern at DiMTEC

The University of the Free State (UFS) is celebrating Youth Month by showcasing the positive influence of the institution on career development. As part of this initiative, we are sharing the stories of UFS alumni who are now working at the university.

Sanchay Kalicharan, ETDP SETA Intern at DiMTEC, shares his UFS journey:

Q: Year of graduation from the UFS:

A: I graduated from the UFS Bloemfontein Campus in 2022.

Q: Qualification obtained from the UFS:

A: I obtained my Postgraduate Diploma in Disaster Management through the Disaster Management Training and Education Centre for Africa (DiMTEC) at the UFS.

Q: Date of joining the UFS as a staff member:

A: In August 2022, I embarked on a new journey as a staff member at the UFS. From the outset, the UFS provided a nurturing and challenging environment that fostered both personal and professional growth. As an intern, I was immersed in a diverse range of tasks and responsibilities that contributed significantly to my understanding of my chosen field.

The experience has been highly rewarding, equipping me with valuable insights and practical skills, while offering an opportunity to make meaningful contributions to the university's community. The camaraderie and support of my colleagues made for a dynamic work culture that drove excellence and innovation. Overall, joining the UFS marked a significant step on my career path.

Q: Initial job title and current job title:

A: In August 2022, I embarked on an enriching journey with the UFS as a PYEI intern at DiMTEC. Over the course of six months, I was deeply immersed in a variety of tasks, honing my skills, and gaining valuable insights into disaster management.

As my initial internship drew to a close in January 2023, a new chapter began. I transitioned into the role of an ETDP SETA intern with DiMTEC. From February 2023 till now, I have been extending my understanding and practical knowledge of the field. Each day brings a new learning opportunity, reinforcing the theoretical concepts I have studied with real-world applications. These successive roles at the UFS have played an integral part in shaping my professional career.

Q: How did the UFS prepare you for the professional world?

A: The UFS prepared me for the professional world in numerous ways. The internships I undertook at DiMTEC provided me with a robust platform to acquire practical skills and insights that are highly valuable in the professional world.

During my time as a PYEI intern, I was exposed to various facets of disaster management. This hands-on experience, paired with guidance from seasoned professionals, allowed me to delve into the complexities of the field and build my competency. Transitioning into the role of an ETDP SETA intern, I was able to further develop my understanding and skills in the disaster management field. The UFS provided continuous opportunities for learning and development, reinforcing theoretical knowledge with practical, real-world experiences.

In addition to the technical skills, the UFS also fostered the growth of soft skills such as teamwork, communication, problem-solving, and leadership, which are paramount in the professional world. Through collaborations, projects, and day-to-day interactions, I learned how to work effectively with diverse individuals, navigate challenges, and lead initiatives. This holistic training at the UFS has equipped me with the tools and confidence to navigate the professional landscape.

Q: What are your thoughts on transitioning from a UFS alumnus to a staff member?

A: Transitioning from a UFS alumnus to a staff member has been an enriching and rewarding journey. As a student, the university provided an excellent foundation of academic knowledge and practical skills. As a staff member, I have had the opportunity to apply and extend this knowledge, further deepening my understanding of my chosen field.

This transition has offered a different perspective on the workings of the institution. While my focus as a student was primarily on learning and personal development, as a staff member I am now contributing to the university's operations and its mission. This has given me a greater appreciation for the efforts that go into running such an institution, and the responsibilities that come with my role.

Being a part of the UFS staff also gives me a unique opportunity to give back to the community that has given so much to me during my student years. It is a chance to contribute to the academic and personal growth of current and future students, just as my teachers and mentors did for me. Overall, the transition has been a fulfilling experience and I look forward to continuing to make a positive impact in my role at the UFS.

Q: Any additional comments about your experience?

A: Throughout my journey at the UFS, both as an alumnus and as a staff member, I have found the environment to be nurturing and inspiring. Each role has brought new challenges and opportunities that have fostered my personal and professional growth.

The transition from being a student to joining the staff was seamless, largely due to the supportive community and culture of the UFS. I have been fortunate to collaborate with and learn from a diverse and talented group of professionals who are deeply committed to their work and the university's mission.

One significant aspect of my experience has been the real-world impact of the work we do at DiMTEC. It is fulfilling to know that our efforts contribute to the broader goal of enhancing disaster management strategies and practices.

Lastly, I greatly appreciate the continuous learning opportunities provided by the UFS. Whether it is through formal training, learning from colleagues, or tackling challenging projects, there is always an opportunity to learn and grow. This commitment to continuous learning is something I value deeply, and it fuels my passion for my work at the UFS.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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