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12 May 2023 | Story Kekeletso Takang | Photo Supplied
Faculty of Education shapes learners’ dreams
Stakeholders forming the multidisciplinary team and a learner from Kgotsofalo Primary School at the event on 21 April 2023, are from the left: Dina Mashiyane, Dr Vusiwana Babane, Ronet Vrey, a learner from Kgotsofalo Primary School, and Prof Bekithemba Dube.

There has been a clarion call within the education sector for primary school intervention strategies. As an institution that invests in education in its surrounding areas and beyond, the University of the Free State (UFS) has heeded the call to impactfully support societal development as outlined in its Vision 130. Through its Faculty of Education, the UFS has adopted the Kgotsofalo Primary School in the Free State to help shape the minds of the learners in this rural school.    

Dr Vusiwana Babane, Lecturer in the Faculty of Education, identified the school – situated about 46 km from the UFS Bloemfontein Campus – as part of a community engagement project that aims to transform the lives of children in low-income communities, in order to eradicate and break the vicious cycle of poverty in their families and communities. The project also seeks to inform stakeholders about the role that higher education institutions can play in supporting farm and rural schools.

Multidisciplinary approach

Prof Bekithemba Dube, acting Head of the Department of Education Foundations in the Faculty of Education, says the initiative with Kgotsofalo Primary School is a culmination of efforts to engage the community around the UFS. “Dr Babane and I visited the school in March 2023 to establish the needs of the school, which could help in planning and exploring intervention strategies. We established that, among others, their needs included motivation for learners, career guidance, library and sports resources. This implied that we needed a multidisciplinary approach. We invited Grade 7 learners from the school to attend motivational and career guidance sessions. We then started collaborating with colleagues from the Education Science Centre, KovsieSport, and the UFS Library and Information Services (Sasol Library) to co-host the learners and for further interventions at the school.”

On 21 April 2023, the learners, teachers, and representatives of the school governing body (SGB) visited the UFS. Hosted at the newly built UFS Education Science Centre, the learners participated in and explored various science experiments. A visit to the UFS library was also part of the package and the learners were treated to motivation, career guidance, and souvenirs from the Faculty of Education, before concluding their visit with a tour to KovsieSport. 

Masontaha Mosuoe, one of the learners who delivered an acceptance speech that brought many to tears, thanked the UFS for the experience. “Today, I would like to thank the UFS for giving our school the opportunity to be here; as you all know, education on the farms is not like the ones in the city. On the farms, children struggle to go to school because the schools are not enough. Thank you for giving us the experience of varsity life and shaping our dreams at a very young age.” 

The Principal of Kgotsofalo Primary School, Mmadikeledi Seepamore, also expressed her gratitude to the university. “Seed was sown and will continue to grow. The experience was educational, fun, and good and changed my learners’ way of thinking.”

Click here for more information on the programmes and other offerings and initiatives in the Faculty of Education.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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