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19 April 2024 | Story André Damons | Photo Charl Devenish
Dr Nashua Naicker
Dr Nashua Naicker, lecturer and Chairperson: Learning and Teaching Committee (SoHRS) in the Department of Optometry, UFS School of Health and Rehabilitation Sciences, graduated on Thursday (April 18) with the degree Doctor of Philosophy in Health Professions Education.

A strong need to improve the general standing of optometry as a profession and to create lifelong learning opportunities for locally trained optometrists beyond what currently exists, is what led Dr Nashua Naicker to pursue a PhD in this field.

Dr Naicker, lecturer, and Chairperson: Learning and Teaching Committee (SoHRS) in the Department of Optometry, UFS School of Health and Rehabilitation Sciences, says he feels an overwhelming sense of relief with a keen sense accomplishment by achieving what he set out to through persistence in the face of adversity.

He graduated on Thursday (18 April) at the Faculty of Health Sciences April graduation ceremony with the degree Doctor of Philosophy in Health Professions Education through the Division of Health Sciences Education. “I am pleased and hope to change the narrative on this new path as an accredited researcher from ‘how long are you going to take to finish?’ to ‘what have you learnt in this journey?’. We are far too focused on chasing a timeline rather than focusing on the contribution that one makes and the self-development in this journey of discovery,” says Dr Naicker. 

His supervisor was Prof Alvin J Munsamy from University of KwaZulu-Natal (UKZN) and co-supervisor Dr CB Written from the UFS.  

Need for educational expansion

His research was focused on establishing a framework for postgraduate programmes in specialty fields of optometry for South Africa. The investigation was carried out with practising optometrists as the primary stakeholders and with optometric academics as the custodians for education and training in the country.

“With an overwhelming need for educational expansion found in this investigation, a conceptual framework was proposed as the innovation to take the profession forward in South Africa. Improving patient care from being upskilled and receiving professional recognition for the additional competencies and proficiencies that would be gained, was the motivating factors identified by optometrists to consider further education and training,” says Dr Naicker.

According to him, being in the educational fraternity for almost two decades and as a former education committee member of the professional board of optometry, he was able to see where the shortcomings were in the profession which set him on this path to pursue this research. With most optometrists in clinical practice and no clinical postgraduate qualifications available except pure research-based qualifications in SA, Dr Naicker explains that this hindered optometrists’ professional trajectory and career path opportunities into various special interest areas. 

“By developing a framework for horizontal articulation pathways towards coursework postgraduate qualifications in various clinical specialty fields, this would be the contribution in addressing the educational gap that would guide higher education institutions in their programme development process. The beneficiaries of this expansion would not only be the health professionals but the patients who access optometric care from the optometrists who would have advanced skills and competencies to deliver comprehensive eye care services.”

Stayed motivated

Dr Naicker says the journey to his PhD was challenging from the outset as the country went into hard lockdown due the COVID-19 pandemic just five weeks after he registered for his PhD. Working on a PhD was not a priority at the time when your survival and that of your loved ones was uncertain as thousands of people fell victim to the coronavirus. Further to this, he continues, multiple changes to his supervisory team and the overhaul and revitalisation of the administration and management of the UFS Division of Health Sciences Education, also impacted his progress in his doctoral research at that time. He had felt despondent after a year of being registered when stability arrived with supervisory assistance that re-ignited his drive to pick up the slack and keep moving forward.

“The words ‘push through it’ were verbalised to me by a stranger I met in passing.  While chatting about research I found those three words to be so profound and with such depth that they resonated with my experience of facing adversity but remaining vigilant to preservere and not drop the baton in the race against time to conclude my research. Gaslighting yourself and questioning your potential to complete a PhD only compounds your procrastination which was all too apparent. The goal is to rise above the self-doubt, brush off the devil with the fork sitting on your shoulder and just ‘push through it’.”

Dr Naicker, who is currently supervising four master’s of optometry students in their research undertaking, as well as undergraduate research projects, says he is in the process of publishing the research manuscripts generated from his PhD and is also part of a task team with the professional Board of Optometry for setting up the board exams for foreign-qualified optometrists. He would also like to work on research involving educating the educators of visually impaired learners.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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