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The first clinical PhD in nuclear medicine completed at the UFS

18 April 2024 | Story Andre Damons | Photo Charl Devenish

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans.

News Archive

Two UFS architecture students won prestigious PG Bison 1.618 Competition

2017-10-26

At the PG Bison 1.618 competition awards ceremony
in Rosebank, were from the left:
Camrin Plaatjes from the University of KwaZulu-Natal;
Stephan Diedericks, winner of the competition;
and Margaux Loubser,
the second-place winner. Both Stephan and
Margaux are studying Architecture at the UFS.
Photo: Supplied

Food that reaches its sell-by date in supermarkets is usually disposed of, but has not yet reached its best-before date. What happens to this food? According to Stephan Diedericks, the answer to this is for this food to be repurposed.

Not only does Stephan want to prevent the waste of food – in a world where food security is a challenge – but he also won the prestigious PG Bison 1.618 Competition with his entry in which he suggests that gourmet meals be prepared from food that has reached its sell-by date, and then be served in the Delta Recycletorium.

Students introduced to park lands in urban areas
Diedericks is a student in the Department of Architecture at the University of the Free State (UFS). Second-place winner in this competition was Margaux Loubser, also a UFS student. Another UFS student, Dehan Kassimatis, was a finalist. They received their awards at a ceremony in Rosebank, Johannesburg, earlier this month.

The competition, now in its 24th year, was created to recognise the future interior and industrial designers, architects, and key decision-makers in the South African construction industry. It is known not only for the prestige it offers its winners, but also for the tradition-defying brief given to the students each year.

According to lecturers Kobus du Preez and Zak Wessels, in the Department of Architecture, the competition introduced the students to parklands in urban areas. He quotes the competition brief: “Rural to urban migration with the development of commercial and residential property elevates the importance of parklands within cities, in creating a refuge from the hustle of daily life. These areas are leveraged to encourage healthier living, community interaction and environmental awareness.”

Learning experience more important than prizes
The site that was the focus of the competition is the Environmental Centre, Delta Park Heritage Precinct in Johannesburg. Students needed to transform this old building into a vibrant gastronomic restaurant. “The theme and style of the restaurant was for the student to choose,” said Du Preez.

Loubser called her restaurant Rooted – a wholefood restaurant. She was influenced by the geometries of the original Art Deco building. Rooted articulates and integrates the space between nature and the building. Similar to an Art Deco painting or poster, the landscape is abstracted into terraces which are used to grow vegetables organically. Vertical green screens soften the divide between the building and its surroundings and it provides shade.

“Our students took their clues from the existing environment and integrated it with a single idea, an abstract concept, which impressed the judges,” Du Preez said.

Although this is a competition that is well reported in the industry press, Du Preez and Wessels agree that the learning experience for students is much more important than winning the contest. The competition’s brief aligned well with the Department of Architecture’s learning content with its urban focus.

Jacques Steyn, a UFS architecture student, came third in the competition in 2015.

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